Ignite Creation Date:
2024-05-06 @ 5:27 PM
Last Modification Date:
2024-10-26 @ 2:29 PM
Study NCT ID:
NCT05311891
Status:
UNKNOWN
Last Update Posted:
2022-05-27
First Post:
2022-03-23
Brief Title:
Variants of SARS-CoV-2 Causing COVID-19 in Africa
Sponsor:
ANRS Emerging Infectious Diseases
Organization:
ANRS Emerging Infectious Diseases
Study Overview
Official Title:
Variants of SARS-CoV-2 in Central and West Africa Frequency of Circulating Viruses and Implications for the Management and Control of the Pandemic
Status:
UNKNOWN
Status Verified Date:
2022-03
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
South-Spike
Brief Summary:
The main objective of this research is to identify and characterize the different molecular variants of SARS-CoV-2 emerging and or circulating in several countries of Sub-Saharan Africa Burkina Faso Côte dIvoire Gabon Mali Chad and Republic of Congo and determine their role in the evolution of the pandemic
Detailed Description:
The main objective of this research is to identify and characterize the different molecular variants of SARS-CoV-2 emerging and or circulating in several countries of Sub-Saharan Africa Burkina Faso Côte dIvoire Gabon Mali Chad and Republic of Congo and determine their role in the evolution of the pandemic
The research will combine retrospective and prospective approaches to determine the evolutionary dynamics of the virus since the start of the pandemic It is planned to sequence the entire Spike protein gene for 1550 viruses and make 300 entire genomes This work will be supplemented by antibody seroneutralization and respiratory transcriptomics tests in order to estimate the immuno-virological response of the COVID-19 disease associated with the identified SARS-CoV-2 variants
The research will combine retrospective and prospective approaches to determine the evolutionary dynamics of the virus since the start of the pandemic It is planned to sequence the entire Spike protein gene for 1550 viruses and make 300 entire genomes This work will be supplemented by antibody seroneutralization and respiratory transcriptomics tests in order to estimate the immuno-virological response of the COVID-19 disease associated with the identified SARS-CoV-2 variants
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None