Ignite Creation Date:
2024-05-06 @ 5:26 PM
Last Modification Date:
2024-10-26 @ 2:29 PM
Study NCT ID:
NCT05308914
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-06-18
First Post:
2022-03-09
Brief Title:
Self-Management and Resilience Trajectories in African American Adults With Hypertension
Sponsor:
Case Western Reserve University
Organization:
Case Western Reserve University
Study Overview
Official Title:
Self-Management and Resilience Trajectories in African American Adults With Hypertension
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hypertension HTN rates have increased worldwide but the most significant increase in the incidence of morbidity and mortality has been in African Americans AA12 43 vs 27 for other US population groups Despite evidence of positive benefits from lifestyle modification healthy diet reduced sodium intake increased physical activity smoking cessation and prescribed antihypertensive therapy AHT many AA with HTN do not adhere to their treatment regimens Consistent effective lifelong self-management is required to sustain optimal BP control and thus reduce morbidity and mortality Self-managing HTN to a blood pressure BP 13080 mm Hg presents challenges such as juggling multiple medications and health care providers dealing with complex recommendations and treatment regimens and coping with negative emotional states Few studies have examined the biopsychosocial mechanisms that foster effective HTN self-management and resilience among AA living with HTN Understanding the mechanisms that influence HTN self-management and resilience in AA holds the promise of new modifiable targets for behavior-change interventions
This study explores the relationship among resilience precursors on hypertension HTN self-management behaviors stress response and the effects that these relationships have on health outcomes-health-related quality of life HRQOL and blood pressure BP in African Americans AA with HTN over a 6-month period
This study explores the relationship among resilience precursors on hypertension HTN self-management behaviors stress response and the effects that these relationships have on health outcomes-health-related quality of life HRQOL and blood pressure BP in African Americans AA with HTN over a 6-month period
Detailed Description:
This study identifies profiles of self-management and the resilience trajectories in AA with HTN can lead to culturally appropriate patient-centered interventions that improve their HTN self-management quality of life and long-term compliance
This study aims to
1 Assess the association among resilience precursors dispositional optimism and resilience emotion regulation stress response physiological cortisol interleukins IL-6 and psychological depression cognitions perceived stress hypertension self management behaviors self-efficacy for chronic disease management medication adherence to antihypertensives and health outcomes HQROL and BP in AA with HTN at baseline and months 3 and 6
2 Determine if stress response mediates the relationship between resilience precursors and health outcomes over time when controlling for risk regulators
3 Determine if self-management behaviors mediates the relationship between resilience precursors and health outcomes over time when controlling for risk regulators
4 Identify resilience trajectory patterns and factors that influence HTN self-management behaviors over time
This study aims to
1 Assess the association among resilience precursors dispositional optimism and resilience emotion regulation stress response physiological cortisol interleukins IL-6 and psychological depression cognitions perceived stress hypertension self management behaviors self-efficacy for chronic disease management medication adherence to antihypertensives and health outcomes HQROL and BP in AA with HTN at baseline and months 3 and 6
2 Determine if stress response mediates the relationship between resilience precursors and health outcomes over time when controlling for risk regulators
3 Determine if self-management behaviors mediates the relationship between resilience precursors and health outcomes over time when controlling for risk regulators
4 Identify resilience trajectory patterns and factors that influence HTN self-management behaviors over time
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None