Ignite Creation Date:
2024-05-05 @ 5:35 PM
Last Modification Date:
2024-10-26 @ 9:33 AM
Study NCT ID:
NCT00484913
Status:
COMPLETED
Last Update Posted:
2007-06-12
First Post:
2007-06-08
Brief Title:
Effects of Abdominal Hot Compresses on Indocyanine Green Elimination in Healthy Subjects
Sponsor:
University Hospital Freiburg
Organization:
University Hospital Freiburg
Study Overview
Official Title:
Effects of Abdominal Hot Compresses on Indocyanine Green Elimination - a Randomized Cross Over Study in Healthy Subjects
Status:
COMPLETED
Status Verified Date:
2007-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
We investigated whether abdominal hot compresses effect hepatic blood flow Our hypothesis was that the hot compresses might either by local vasomotor-reflex or by decreasing the tone of the sympathetic nerve system increase hepatic blood flow
Detailed Description:
Abdominal hot compresses are traditionally used by patients with liver diseases as self help This study investigated the effect of abdominal hot compresses on hepatic blood flow measured by elimination of indocyanine green ICG a non-toxic green dye It was presumed that abdominal hot compresses increase hepatic blood flow either by local vasomotor-reflex or by decreasing the tone of the sympathetic nerve system
In healthy volunteers ICG elimination was measured with and without hot compress at two investigations in a weekly interval At each investigation ICG was injected as bolus after a rest period of 10 minutes After the injection blood was taken in regular intervals for analysis of ICG concentration over a period of 40 minutes and half life was calculated
The time interval between the investigations was 8 days the sequence was randomly assigned
In healthy volunteers ICG elimination was measured with and without hot compress at two investigations in a weekly interval At each investigation ICG was injected as bolus after a rest period of 10 minutes After the injection blood was taken in regular intervals for analysis of ICG concentration over a period of 40 minutes and half life was calculated
The time interval between the investigations was 8 days the sequence was randomly assigned
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None