Ignite Creation Date:
2024-05-05 @ 5:34 PM
Last Modification Date:
2024-10-26 @ 9:33 AM
Study NCT ID:
NCT00489437
Status:
COMPLETED
Last Update Posted:
2013-09-10
First Post:
2007-06-19
Brief Title:
Heparin-Induced Thrombocytopenia Score Card Study
Sponsor:
McMaster University
Organization:
McMaster University
Study Overview
Official Title:
Improving the Diagnosis of Heparin-Induced Thrombocytopenia Utility of the 4Ts Score and Evaluation of New Rapid Assays
Status:
COMPLETED
Status Verified Date:
2013-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Main Research Question
Can two new types of test one called the 4Ts score and the other called a rapid assay help doctors correctly identify which patients are unlikely to have heparin-induced thrombocytopenia HIT
HIT is a severe allergic reaction to the blood thinner heparin This allergic reaction can lead to heart attacks strokes limb amputations and death Because heparin is one of the most commonly used drugs in the hospital setting it is very important that the investigators are able to correctly identify who can safely continue to take heparin and who cannot
It can be very difficult to diagnose HIT because it can look like many other medical conditions and the best laboratory tests for HIT are difficult to run and only available at specialized centres
It would be very helpful if doctors had tests they could use that would tell them quickly and accurately which patients with symptoms that look like HIT really do have HIT and require urgent treatment with another type of blood thinner and which patients are very unlikely to have HIT and could continue to take heparin safely In this study the investigators will compare the 4Ts score a scoring system that assigns points to the presence or absence of specific clinical features and a rapid laboratory test with the old laboratory test to find out if one or both of these types of tests are useful for telling doctors which patients have HIT and which patients dont have HIT
Can two new types of test one called the 4Ts score and the other called a rapid assay help doctors correctly identify which patients are unlikely to have heparin-induced thrombocytopenia HIT
HIT is a severe allergic reaction to the blood thinner heparin This allergic reaction can lead to heart attacks strokes limb amputations and death Because heparin is one of the most commonly used drugs in the hospital setting it is very important that the investigators are able to correctly identify who can safely continue to take heparin and who cannot
It can be very difficult to diagnose HIT because it can look like many other medical conditions and the best laboratory tests for HIT are difficult to run and only available at specialized centres
It would be very helpful if doctors had tests they could use that would tell them quickly and accurately which patients with symptoms that look like HIT really do have HIT and require urgent treatment with another type of blood thinner and which patients are very unlikely to have HIT and could continue to take heparin safely In this study the investigators will compare the 4Ts score a scoring system that assigns points to the presence or absence of specific clinical features and a rapid laboratory test with the old laboratory test to find out if one or both of these types of tests are useful for telling doctors which patients have HIT and which patients dont have HIT
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None