Ignite Creation Date:
2024-05-05 @ 5:34 PM
Last Modification Date:
2024-10-26 @ 9:33 AM
Study NCT ID:
NCT00485784
Status:
COMPLETED
Last Update Posted:
2014-08-28
First Post:
2007-06-12
Brief Title:
Interest of Circulating Endothelial Biomarkers in Vascular Pregnancy Complications
Sponsor:
Assistance Publique Hopitaux De Marseille
Organization:
Assistance Publique Hopitaux De Marseille
Study Overview
Official Title:
Interest of Circulating Endothelial Biomarkers in Vascular Pregnancy Complications
Status:
COMPLETED
Status Verified Date:
2014-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a prospective multicentric study including four clinical units of Gynecology and Obstetrics 3 public health hospitals and one private team one research team in Hematology and one Center of Clinical investigation CIC
The objective is to identify beside the pregnancy in a population of patients with a preeclampsia PE with fetus presenting with growth restriction IUGR and a fetal demise FD a modification of circulating endothelial biomarkers compared with normal pregnancy
We want to understand better the physiopathology of preeclampsia and propose to patients with an endothelial dysfunction a early prevention of preeclampsia
Patients will be tested 3 times At the pregnancy events then 8 weeks and 12 months after the birth
Four groups will be constituted among patients PE IUGR FD and normal pregnancy
Normal pregnancy will be tested as controls The next pregnancy presenting in the unit to medical pregnancy follow up will be invited to participate
The main judgment criteria will be the levels of endothelial microparticles 8 weeks after the event
The study will last 3 years The number of patient to include is 280
The objective is to identify beside the pregnancy in a population of patients with a preeclampsia PE with fetus presenting with growth restriction IUGR and a fetal demise FD a modification of circulating endothelial biomarkers compared with normal pregnancy
We want to understand better the physiopathology of preeclampsia and propose to patients with an endothelial dysfunction a early prevention of preeclampsia
Patients will be tested 3 times At the pregnancy events then 8 weeks and 12 months after the birth
Four groups will be constituted among patients PE IUGR FD and normal pregnancy
Normal pregnancy will be tested as controls The next pregnancy presenting in the unit to medical pregnancy follow up will be invited to participate
The main judgment criteria will be the levels of endothelial microparticles 8 weeks after the event
The study will last 3 years The number of patient to include is 280
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None