Ignite Creation Date:
2024-05-05 @ 5:33 PM
Last Modification Date:
2024-10-26 @ 9:33 AM
Study NCT ID:
NCT00484081
Status:
COMPLETED
Last Update Posted:
2007-06-08
First Post:
2007-06-06
Brief Title:
Microdissection Testicular Sperm Extraction MicroTESE and IVF-ICSI Outcome in Non-Obstructive Azoospermia NOA
Sponsor:
Clinic and Research Center in Human Reproduction Roger Abdelmassih
Organization:
Clinic and Research Center in Human Reproduction Roger Abdelmassih
Study Overview
Official Title:
Prospective Evaluation of Microdissection Testicular Sperm Extraction in Non-Obstructive Azoospermic Men and Their IVF-ICSI Related Outcomes at ART Treatment
Status:
COMPLETED
Status Verified Date:
2007-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
We evaluated the application of surgical testicular exploration with the aid of a microscope MictoTESE to increase the chances of obtaining sperm in men with impaired sperm production a condition known as non-obstructive azoospermia
We also evaluated the outcomes of these couples when the sperm obtained were used in ICSI Intracytoplasmic Sperm Injection during assisted reproductive technology treatment
We believe that excellent results may be obtained with the use of the following techniques in the treatment of couples where non-obstructive azoospermia is a significant cause
We also evaluated the outcomes of these couples when the sperm obtained were used in ICSI Intracytoplasmic Sperm Injection during assisted reproductive technology treatment
We believe that excellent results may be obtained with the use of the following techniques in the treatment of couples where non-obstructive azoospermia is a significant cause
Detailed Description:
Men diagnosed with non-obstructive azoospermia and seeking assisted reproductive technology treatment ART are candidates for surgical sperm retrieval with the aid of microdissection We believe that this approach may currently be the best option for these subjects
We evaluated our surgical sperm retrieval rate associated to their serum LH FSH TOTAL TESTOTERONE and PROLACTIN levels pre-operative testicular volume and also compared to the post-operative histological analysis of fixed testicular tissue specimens collected during the procedure stained with haematoxylin and eosin
We also evaluated the outcomes using ICSI based ART for these couples observing mean ICSI and fertilized oocytes number and quality of embryos transferred implantation and pregnancy rates
We evaluated our surgical sperm retrieval rate associated to their serum LH FSH TOTAL TESTOTERONE and PROLACTIN levels pre-operative testicular volume and also compared to the post-operative histological analysis of fixed testicular tissue specimens collected during the procedure stained with haematoxylin and eosin
We also evaluated the outcomes using ICSI based ART for these couples observing mean ICSI and fertilized oocytes number and quality of embryos transferred implantation and pregnancy rates
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None