Viewing Study NCT00476879



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Study NCT ID: NCT00476879
Status: COMPLETED
Last Update Posted: 2008-08-12
First Post: 2007-05-21

Brief Title: Growth Hormone During FastingSignaltransduktion in Muscle and Adipose Tissue and Changes in Intrahepatic Lipid Content
Sponsor: University of Aarhus
Organization: University of Aarhus

Study Overview

Official Title: Growth Hormone During Fasting Signaltransduktion in Muscle and Adipose Tissue Consequence of Growth Hormone Receptor Antagonist Quantification of Intrahepatic Lipid Content Based on MR Scanning
Status: COMPLETED
Status Verified Date: 2008-08
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The purpose of this study is to examine the effects of growth hormone during fasting in healthy lean men
Detailed Description: During fasting the human body is known to metabolize relatively large amounts of fat in the expense of proteins and glucose Partly this shift in metabolism is caused by increasing GH secretion but exactly how growth hormone exerts these effects remains to be further investigated

10 healthy lean young men are studied at 4 different occasions in a randomized single-blinded cross-over study 1 after 12 hours of fasting GH bolus 2 after 36 hours of fasting GH bolus 3 after 36 hours saline 4 after 36 hours of fasting Somavert

Aim

to study the signal transduction in muscle and fat tissue
to study the metabolism during fasting
to study the intrahepatic fat content using magnetic resonance techniques

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None