Ignite Creation Date:
2024-05-06 @ 5:13 PM
Last Modification Date:
2024-10-26 @ 2:24 PM
Study NCT ID:
NCT05231226
Status:
NOT_YET_RECRUITING
Last Update Posted:
2022-02-09
First Post:
2021-12-30
Brief Title:
Timing of Complete Revascularization in Patients With ST-segment Elevation Myocardial Infarction And Multivessel Disease
Sponsor:
Beijing Anzhen Hospital
Organization:
Beijing Anzhen Hospital
Study Overview
Official Title:
Timing of Complete Revascularization in Patients With ST-segment Elevation Myocardial Infarction And Multivessel Disease-A Multi-center Randomized Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2022-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TERMINAL
Brief Summary:
At present the two treatment strategies of opening non infarct related arteries non IRA simultaneously or by stages after emergency percutaneous coronary intervention PCI in patients with acute ST segment elevation myocardial infarction STEMI complicated with multi vessel disease MVD are still controversial In our previous retrospective analysis there was no significant difference between complete revascularization CR and staged CR at Anzhen Hospital in the cases of cardiac death reinfarction stroke proportion of revascularization and hospitalization rate of heart failure
Detailed Description:
The literature reports on the benefits of two CR strategies of opening non IRA simultaneously or by stages after IRA treatment in STEMI patients are inconsistent This study intends to enroll 426 cases and divide into two groups to verify whether the occurrence of major cardiovascular adverse events all-cause death nonfatal myocardial infarction ischemia driven revascularization and heart failure in one year in immediately open non-IRA after successful emergency PCI of infarct related arteries in STEMI patients with MVD group is not inferior to staged within 45 days CR group It can accumulate more evidence-based medical basis for the selection of better treatment schemes so as to formulate optimized treatment schemes for clinic To study when to open meaningful non IRA in acute STEMI complicated with MVD is of great guiding significance for CR after acute myocardial infarction At the same time it has important social significance and economic value for delaying or preventing cardiovascular events
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None