Ignite Creation Date:
2025-12-24 @ 12:44 PM
Ignite Modification Date:
2025-12-30 @ 9:07 AM
Study NCT ID:
NCT03595761
Status:
COMPLETED
Last Update Posted:
2018-07-26
First Post:
2017-07-06
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Meningitis With Cerebral Vasculitis in Children
Sponsor:
University Hospital, Montpellier
Organization:
Study Overview
Official Title:
Retrospective Study About 17 Cases of Child With Bacterial Meningitis Coupled With Cerebral Vasculitis
Status:
COMPLETED
Status Verified Date:
2017-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Purulent meningitis are life-threatening diseases in childhood. Cerebral vasculitis have been described in bacterial meningitis, but poor is known about their physiology and their impact on outcome.
The investigators decide to realize a retrospective mono-centric study carried out at Montpellier university hospital which looks back at a 7-year study(2009-2016).
The Investigators selected purulent meningitis cases based on the bacteriological data provided by the HDB (hospital data base). The Investigators divides in two groups : Group A if patients present a cerebral vasculitis ( radiologic diagnostic by RMI or tomodensitometry), in all, cases the diagnosis of vasculitis was confirmed by a radiologist specialised in neuropaediatrics by a second reading;Group B purulent meningitis with a cerebral vasculitis imaging.
Tuberculous meningitis, meningitis in CSF shunt, and in patients having chemotherapy were excluded.
The investigators report clinical and biological finding, inflammatory marker at the onset. The Investigators register also the clinical evolution and sequelae
The investigators decide to realize a retrospective mono-centric study carried out at Montpellier university hospital which looks back at a 7-year study(2009-2016).
The Investigators selected purulent meningitis cases based on the bacteriological data provided by the HDB (hospital data base). The Investigators divides in two groups : Group A if patients present a cerebral vasculitis ( radiologic diagnostic by RMI or tomodensitometry), in all, cases the diagnosis of vasculitis was confirmed by a radiologist specialised in neuropaediatrics by a second reading;Group B purulent meningitis with a cerebral vasculitis imaging.
Tuberculous meningitis, meningitis in CSF shunt, and in patients having chemotherapy were excluded.
The investigators report clinical and biological finding, inflammatory marker at the onset. The Investigators register also the clinical evolution and sequelae
Detailed Description:
Meningitis steel are a cause of death in childhood. Cerebral complication are often responsable of poor prognosis. One of these complication vasculitis is steel not weel understood. There are only few study about it on children.
It is a retrospective study about 17 cases of chil which bacterial meningitis coupled wiethe cerebral vasculitis, the Investigators will describe epidemiology, bacteriology, evolution and corticosteroid treatment in this patients.
It is a retrospective study about 17 cases of chil which bacterial meningitis coupled wiethe cerebral vasculitis, the Investigators will describe epidemiology, bacteriology, evolution and corticosteroid treatment in this patients.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: