Ignite Creation Date:
2024-05-06 @ 5:10 PM
Last Modification Date:
2024-10-26 @ 2:23 PM
Study NCT ID:
NCT05215366
Status:
UNKNOWN
Last Update Posted:
2022-01-31
First Post:
2022-01-18
Brief Title:
Value of Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital
Sponsor:
Sohag University
Organization:
Sohag University
Study Overview
Official Title:
Value of Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital
Status:
UNKNOWN
Status Verified Date:
2022-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Febrile seizures are one of the most common clinical diseases in pediatric neurology It occurs between 6 months and 6 years of age and occurs in 2-5 of children According to the age frequency duration and type of seizures FS is divided into simple febrile seizures and complex febrile seizures Differentiation between febrile seizures and non-ictal events associated with fever such as shivering or dizziness is challenging Therefore precise diagnosis of FS after paroxysmal episodes associated with fever is often hindered by the lack of an objective biomarker With the widespread application of technologies such as molecular biology in medicine some biomarkers for predicting or diagnosing FS have attracted attention Imuekemhe et al in 1989 and 1996 found that lactic acid in the serum and cerebrospinal fluid of children with FS was significantly increased Arginin-vasopressin hormone AVP released by the pituitary gland has been shown to be involved in the thermoregulatory response to fever and convulsions Although AVP is unstable in the peripheral blood and therefore unsuited for diagnostic use the C-terminal portion of the AVP precursor copeptin has been recognized as a robust marker of AVP secretion Wellman et al found that the serum copeptin and Von Willebrand factor of children with FS were significantly higher than those of the control group
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None