Ignite Creation Date:
2024-05-06 @ 5:07 PM
Last Modification Date:
2024-10-26 @ 2:22 PM
Study NCT ID:
NCT05204407
Status:
RECRUITING
Last Update Posted:
2024-07-09
First Post:
2022-01-11
Brief Title:
Luteolin for the Treatment of People With Schizophrenia
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Luteolin for the Treatment of People With Schizophrenia
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Luteolin is a natural product found in foods such as celery green pepper parsley and chamomile tea It has been found to have anti-cancer anti-oxidant and anti-inflammatory properties The purpose of this study is to determine if luteolin helps improve symptoms of schizophrenia
Detailed Description:
The study is a 12-week double-blind placebo-controlled parallel group randomized clinical trial of the efficacy of luteolin for the treatment of people with schizophrenia who present with residual symptoms and cognitive impairments The study will be conducted at two sites The Maryland Psychiatric Research Center MPRC and the University of California Los Angeles UCLA Participants will be randomized to either 300mg BID luteolin three 100mg capsules or placebo We hypothesize that luteolin will have significant beneficial effects on global psychopathology and cognitive impairments decrease antioxidant stress and levels of inflammatory markers and that improvement in global psychopathology and cognition will be associated with changes in the oxidative stress and inflammatory measures We also hypothesize that luteolin will be associated with improvements in positive and negative symptoms of schizophrenia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None