Ignite Creation Date:
2024-05-06 @ 5:07 PM
Last Modification Date:
2024-10-26 @ 2:23 PM
Study NCT ID:
NCT05209204
Status:
COMPLETED
Last Update Posted:
2022-01-26
First Post:
2022-01-07
Brief Title:
Anterior Chamber Angle Examination in Angle Closure Suspect Patients
Sponsor:
Minia University
Organization:
Minia University
Study Overview
Official Title:
Anterior Chamber Angle Examination in Angle Closure Suspect Patients
Status:
COMPLETED
Status Verified Date:
2022-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to detect PACG suspects using both AS OCT and Scheimpflug imaging
Detailed Description:
Glaucoma is a form of progressive optic neuropathy and is one of the leading causes of preventable blindness worldwide The average life span is increasing leading to more individuals developing glaucoma as well as having the disease longer which makes early detection and management very important1 Glaucoma is characterized by loss of retinal ganglion cells RGCs recognized as optic nerve head ONH changes corresponding visual field VF defects and retinal nerve fiber layer RNFL loss At least 40 of RGCs are lost before the VFs show a defect hence the emphasis on early diagnosis in the stage of glaucoma suspect2 There are two types of glaucoma suspect Primary Open angle and primary angle closure suspect3 Primary angle-closure PAC suspects can be detected by the following the trabecular meshwork can only be seen in 180º or less of anterior chamber angle AC by gonioscopy the intraocular pressureIOP remains within normal limits and no structural damage to the optic nerve is present4 Time domain Optical coherence tomography TD-OCT was initially designed to image the posterior segment and retina but its capability to generate cross-sectional images of internal biological structures without contacting the ocular surface was quickly adapted to visualize the anterior segment and cornea5
Spectral domain anterior segment OCT SD-OCT technology allow visualizing the anterior chamber angle of the eye with high speed and high resolution Spectral-domain OCTSD OCT instruments working at 840 nm can reliably identify fine angle structures such as Schwalbes line6 Scheimpflug imaging also offers non-contact imaging of the anterior segment Although Scheimpflug photography cannot fully visualize the entire angle the software available on the Pentacam system Oculus Optikgeräte Wetzlar Germany provides extrapolated measurements of the anterior chamber volume ACV which have shown promise in screening for narrow angles7
Spectral domain anterior segment OCT SD-OCT technology allow visualizing the anterior chamber angle of the eye with high speed and high resolution Spectral-domain OCTSD OCT instruments working at 840 nm can reliably identify fine angle structures such as Schwalbes line6 Scheimpflug imaging also offers non-contact imaging of the anterior segment Although Scheimpflug photography cannot fully visualize the entire angle the software available on the Pentacam system Oculus Optikgeräte Wetzlar Germany provides extrapolated measurements of the anterior chamber volume ACV which have shown promise in screening for narrow angles7
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None