Ignite Creation Date:
2024-05-05 @ 5:31 PM
Last Modification Date:
2024-10-26 @ 9:33 AM
Study NCT ID:
NCT00476489
Status:
UNKNOWN
Last Update Posted:
2007-05-22
First Post:
2007-05-21
Brief Title:
Does Topical Steroid Treatment Impair the Adrenal Function
Sponsor:
HaEmek Medical Center Israel
Organization:
HaEmek Medical Center Israel
Study Overview
Official Title:
Low Dose 1mcg ACTH Stimulation Test for Assessment of the Hypothalamo-Pituitary- Adrenal Axis in Patients Treated With Topical Corticosteroids
Status:
UNKNOWN
Status Verified Date:
2007-05
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine if topical steroids treatment for different skin diseases suppress the adrenal cortisol production
Detailed Description:
Adrenocortical suppression is a potential complication of systemic corticosteroid treatement but also of non systemic therapy like topical therapy
The normalcy of hypothalamic-pituitary-adrenal axis HPA axis of patients with chronic skin diseases like atopic dermatitis pemphigus or psoriasis which are treated with topical steroids will be assessed with the low dose 1mcg adrenocortocotropin ACTH stimulation test During this test serum cortisol levels are measured before 30 and 60 mn after intravenous administration of 1mcg of ACTH synacthenThe results will be compared with age and sex matched subjects with normal HPA axis as assessed by low dose ACTH stimulation test
The normalcy of hypothalamic-pituitary-adrenal axis HPA axis of patients with chronic skin diseases like atopic dermatitis pemphigus or psoriasis which are treated with topical steroids will be assessed with the low dose 1mcg adrenocortocotropin ACTH stimulation test During this test serum cortisol levels are measured before 30 and 60 mn after intravenous administration of 1mcg of ACTH synacthenThe results will be compared with age and sex matched subjects with normal HPA axis as assessed by low dose ACTH stimulation test
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None