Ignite Creation Date:
2024-05-05 @ 5:31 PM
Last Modification Date:
2024-10-26 @ 9:32 AM
Study NCT ID:
NCT00471458
Status:
COMPLETED
Last Update Posted:
2007-05-10
First Post:
2007-05-09
Brief Title:
Follow-up Study of the RAI-Treated Hyperthyroid Patients
Sponsor:
Tampere University
Organization:
Tampere University
Study Overview
Official Title:
Follow-up Study of Hyperthyroid Patients Treated With RAI in 1965-2002 Morbidity in Long-Term Follow-up
Status:
COMPLETED
Status Verified Date:
2007-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Previous studies of hyperthyroid patients suggest that they remain at increased risk of cardiovascular morbidity after restoring euthyroidism
The study objective is to compare the rate and causes of hospitalization of hyperthyroid patients treated with radioactive iodine RAI with those of an age- and gender-matched reference population in a long-term follow-up study
The study objective is to compare the rate and causes of hospitalization of hyperthyroid patients treated with radioactive iodine RAI with those of an age- and gender-matched reference population in a long-term follow-up study
Detailed Description:
A population-based cohort study was conducted among 2611 hyperthyroid patients treated with RAI between 1969 and 2002 in Tampere University Hospital and among 2611 reference subjects A reference group was randomly selected with an age- and gender-matched control subject identified for each patient from the Population Register Centre The control subject had to be alive at the time when the patient received the first RAI treatment
The causes of hospitalization as well as the diagnosis and date of hospital admission were obtained from the nationwide Hospital Discharge Register HILMO maintained by the Research and Development Centre for Welfare and Health STAKES using a computerized record linkage with the personal identification number as the key The HILMO database covers all dates and causes of hospitalization hospital admission requiring an overnight stay of the Finnish citizens since January 1969 New events were analyzed as the main outcome including only the first hospitalization due to a given indication The special focus was on the cardiovascular morbidity
The causes of hospitalization as well as the diagnosis and date of hospital admission were obtained from the nationwide Hospital Discharge Register HILMO maintained by the Research and Development Centre for Welfare and Health STAKES using a computerized record linkage with the personal identification number as the key The HILMO database covers all dates and causes of hospitalization hospital admission requiring an overnight stay of the Finnish citizens since January 1969 New events were analyzed as the main outcome including only the first hospitalization due to a given indication The special focus was on the cardiovascular morbidity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None