Ignite Creation Date:
2024-05-06 @ 5:02 PM
Last Modification Date:
2024-10-26 @ 2:21 PM
Study NCT ID:
NCT05178914
Status:
RECRUITING
Last Update Posted:
2024-06-24
First Post:
2021-10-20
Brief Title:
Personalized Medicine Using Coronary Microvascular Function Measured in Patient With Percutaneous Coronary Intervention in Angina
Sponsor:
University Hospital Grenoble
Organization:
University Hospital Grenoble
Study Overview
Official Title:
Personalized Medicine Using Coronary Microvascular Function Measured in Patient With Percutaneous Coronary Intervention in Angina
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DECISIONING
Brief Summary:
The evidence demonstrating the importance of coronary microcirculation in the management of patients with coronary artery disease is growing For example in recent years a number of studies have demonstrated that the presence of coronary microvascular disease CMVD contributes to increased cardiovascular morbidity and mortality independent of the extent and severity of coronary epicardial disease The index of microcirculatory resistance IMR is an invasive index proposed for the diagnosis of CMVD The ability of IMR to motivate therapeutic changes in order to subsequently reduce symptoms and improves the quality of life of our patients with stable coronary artery disease CAD was recently demonstrated The prognostic value of IMR has also been shown in stable CAD with PCI Thus after optimal epicardial evaluation and if necessary revascularization according to FFR IMR could represent a tool for personalized medicine adapted to the presence of severe CMVD
The aim of the study is to demonstrate a positive effect of personalized medicine on angina in patients with epicardial coronary network lesion assessment by FFR and with significant CMVD assessed by IMR
The aim of the study is to demonstrate a positive effect of personalized medicine on angina in patients with epicardial coronary network lesion assessment by FFR and with significant CMVD assessed by IMR
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None