Ignite Creation Date:
2024-05-06 @ 4:55 PM
Last Modification Date:
2024-10-26 @ 2:18 PM
Study NCT ID:
NCT05135143
Status:
COMPLETED
Last Update Posted:
2021-11-30
First Post:
2021-10-25
Brief Title:
Role of Antioxidants in the Reduction of Oxidative Stress in Infertile Patients
Sponsor:
University of Tetova
Organization:
University of Tetova
Study Overview
Official Title:
Role of Antioxidants in the Reduction of Oxidative Stress in Infertile Patients
Status:
COMPLETED
Status Verified Date:
2021-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OAT
Brief Summary:
Numerous studies verify that the majority of cases of male infertility belong to the group diagnosed with oligoasthenoteratozoospermia OAT which means a decrease in the number of sperm in the ejaculate to 15 million ml reduced sperm motility of the spermatozoa and morphological disorders of the neck or tail of the sperm
Genuine scientific studies can not pinpoint the cause of these changes however recent advances in science shed light on this issue by confirming the reason which is as a result of the action of free radicals - oxidative stress
Genuine scientific studies can not pinpoint the cause of these changes however recent advances in science shed light on this issue by confirming the reason which is as a result of the action of free radicals - oxidative stress
Detailed Description:
The enlightenment project in the field of male infertility in North Macedonia will include a wide team of students general practitioners assistants professors of pre-clinical subjects professors and specialists in the field of gynecology urology and andrologists The involvement of such a large number of professionals once again verifies the seriousness and determination that this scientific project has
Investigators hope to contribute generously to
1 Identifying new cases and taking measures early in order to overcome fertilization problems
2 For the first time in North Macedonia there will be a more accurate picture of the prevalence of male infertility
3 Expanding current scientific knowledge about the role of oxidative stress its laboratory evaluation and the impact of antioxidant supplements
4 Standardization of doses and type of antioxidant supplements that will be used during the realization of this dissertation and evaluation of their clinical effect in men with OAT
5 After the implementation of antioxidant therapy investigators expect that the results of live births and spontaneous pregnancies will increase while the number of miscarriages will decrease
6 Acquisition of knowledge on laboratory and clinical evaluation techniques of infertile men which would later lead to the establishment of an andrological laboratory Investigators anticipate this laboratory to function within the Faculty of Medical Sciences where all procedures will be performed from diagnosis to the operation of assisted reproduction techniques TRA This in addition to the material benefit for the benefit of the University of Tetova also has a benefit in terms of staff which will be professionalized and trained during the realization of this dissertation
Investigators hope to contribute generously to
1 Identifying new cases and taking measures early in order to overcome fertilization problems
2 For the first time in North Macedonia there will be a more accurate picture of the prevalence of male infertility
3 Expanding current scientific knowledge about the role of oxidative stress its laboratory evaluation and the impact of antioxidant supplements
4 Standardization of doses and type of antioxidant supplements that will be used during the realization of this dissertation and evaluation of their clinical effect in men with OAT
5 After the implementation of antioxidant therapy investigators expect that the results of live births and spontaneous pregnancies will increase while the number of miscarriages will decrease
6 Acquisition of knowledge on laboratory and clinical evaluation techniques of infertile men which would later lead to the establishment of an andrological laboratory Investigators anticipate this laboratory to function within the Faculty of Medical Sciences where all procedures will be performed from diagnosis to the operation of assisted reproduction techniques TRA This in addition to the material benefit for the benefit of the University of Tetova also has a benefit in terms of staff which will be professionalized and trained during the realization of this dissertation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None