Ignite Creation Date:
2024-05-06 @ 4:54 PM
Last Modification Date:
2024-10-26 @ 2:18 PM
Study NCT ID:
NCT05124015
Status:
COMPLETED
Last Update Posted:
2021-11-17
First Post:
2021-11-15
Brief Title:
Exercise Capacity Respiratory Muscle Strength Dyspnea and Physical Activity in Pediatric Pulmonary Arterial Hypertension
Sponsor:
Gazi University
Organization:
Gazi University
Study Overview
Official Title:
Exercise Capacity Respiratory Muscle Strength Pulmonary Function Dyspnea and Physical Activity in Pediatric Pulmonary Arterial Hypertension
Status:
COMPLETED
Status Verified Date:
2021-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary aim of this study was to evaluate exercise capacity respiratory muscle strength pulmonary function dyspnea and physical activity levels in pediatric PAH patients and compare them with healthy controls
The secondary aim of the study was To investigate the relationship of dyspnea with exercise capacity respiratory muscle strength respiratory functions physical activity and blood count parameters in pediatric PAH patients
The secondary aim of the study was To investigate the relationship of dyspnea with exercise capacity respiratory muscle strength respiratory functions physical activity and blood count parameters in pediatric PAH patients
Detailed Description:
Pulmonary arterial hypertension PAH is a mean pulmonary artery pressure of 25 mmHg or more at rest Since the diagnosis of PAH can be made mostly in the late phase of the disease severe functional and hemodynamic problems are prevalent in patients In addition patients commonly present with dyspnea fatigue weakness general exercise intolerance chest pain syncope and abdominal distension These signs and symptoms are due to reduced oxygen consumption and decreased cardiac output Activity dyspnea is evident in patients in the early stages of the disease There is limited number of studies in pediatric PAH patients investigating exercise intolerance While the cardiopulmonary exercise test can be safely performed in pediatric PAH patients the six-minute walk test is both an independent predictor of prognosis and reflects the severity of the disease in these patients However there are no studies in the literature investigating and comparing exercise capacity respiratory muscle strength respiratory functions dyspnea and physical activity levels in pediatric PAH patients compared to age- and sex-matched healthy children For this reason in this study the level of physical impairments of children with pediatric PAH was investigated for the first time compared to healthy children In addition there has been no study in the literature investigated the relationship between dyspnea which can be seen significantly from the early stages of the disease in pediatric PAH patients with exercise capacity respiratory function respiratory muscle strength physical activity levels and blood count parameters
It is a cross-sectional study At least 15 PAH patients and 15 age-and sex-matched healthy controls were aimed to include in the study Individuals exercise capacity using six minute walk test respiratory muscle strength using a mouth pressure device pulmonary function using spirometry dyspnea using Modified Borg scale physical activity using multi-sensory activity monitor were evaluated The assessments were completed in two days
It is a cross-sectional study At least 15 PAH patients and 15 age-and sex-matched healthy controls were aimed to include in the study Individuals exercise capacity using six minute walk test respiratory muscle strength using a mouth pressure device pulmonary function using spirometry dyspnea using Modified Borg scale physical activity using multi-sensory activity monitor were evaluated The assessments were completed in two days
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None