Ignite Creation Date:
2024-05-05 @ 5:30 PM
Last Modification Date:
2024-10-26 @ 9:32 AM
Study NCT ID:
NCT00466609
Status:
COMPLETED
Last Update Posted:
2017-10-30
First Post:
2007-04-26
Brief Title:
Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment
Sponsor:
University of Sao Paulo
Organization:
University of Sao Paulo
Study Overview
Official Title:
Pharmacological Augmentation Strategies for Obsessive Compulsive Disorder Patients Non-respondent to First Line Medication Treatment a Double Blind Placebo Controlled Study
Status:
COMPLETED
Status Verified Date:
2017-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EPMTOC
Brief Summary:
This will be a controlled randomized double-blind and double-dummy study on the treatment augmentation strategy for obsessive compulsive disorder patients non-respondent to first line pharmacological treatment The investigators will compare fluoxetine maintenance at maximum dosage for additional 12 weeks the association of fluoxetine with quetiapine and the association of fluoxetine with clomipramine
Detailed Description:
Arm 1 SSRI Fluoxetine 40mg once a day Clomipramine 75mg once a day
Arm 2 SSRI Fluoxetine 40mg once a day Quetiapine 200mg once a day
Arm 3 SSRI Fluoxetine 80mg once a day Placebo once a day
or maximum tolerated dose
We hypothesize that quetiapine and clomipramine will be effective augmentation strategies for resistant OCD patients in comparison to placebo
Arm 2 SSRI Fluoxetine 40mg once a day Quetiapine 200mg once a day
Arm 3 SSRI Fluoxetine 80mg once a day Placebo once a day
or maximum tolerated dose
We hypothesize that quetiapine and clomipramine will be effective augmentation strategies for resistant OCD patients in comparison to placebo
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 200555628-08 | OTHER_GRANT | FAPESP | None |