Ignite Creation Date:
2024-05-06 @ 4:53 PM
Last Modification Date:
2024-10-26 @ 2:18 PM
Study NCT ID:
NCT05125328
Status:
COMPLETED
Last Update Posted:
2024-03-21
First Post:
2021-10-11
Brief Title:
ANI and Remifentanil in Skull Pin Fixation
Sponsor:
Kaohsiung Medical University Chung-Ho Memorial Hospital
Organization:
Kaohsiung Medical University Chung-Ho Memorial Hospital
Study Overview
Official Title:
To Explore the Optimal Dose of Remifentanil for Skull Pin Fixation in Intracranial Surgery
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Forty patients were enrolled and all patients used total intravenous anesthesia remifentanil-propofol based total intravenous analgesia as anesthesia induction and maintenance According to the preliminary data of this department patients who underwent intracranial surgery for skull pin fixation used remifentanil 50-60 ngml while the hemodynamics is relatively stable Therefore when this plan is implemented the patient needs to be under the same depth of anesthesia monitored by electroencephalography maintaining a value of 40-60 first start with remifentanil 60 ngml and use the up and down method as adjust 05 ngml of concentration of remifentanil each time An Analgesia Nociception IndexANI lower than 30 and hyperdynamics the increased heart rateHR and mean blood pressureMBP up 20 of baseline or HR100bpm and arterial blood pressureABP180100mmHg indicates insufficient analgesia therefore increase it by 05 ngml an ANI higher than 30 and stable hemodynamics the changes of HR and MBP within 20 of baseline or HR50bpm and ABP9050mmHg indicates that analgesia is acceptable and the next patient will decrease it by 05 ngml during skull pin fixation
Data collection Heart Rate Measure blood pressure Analgesia Nociception Index Bispectral index concentrations of propofol and remifentanil before 2 mins during 5 and 15 mins of skull pin fixation were recorded and analyzed
Data collection Heart Rate Measure blood pressure Analgesia Nociception Index Bispectral index concentrations of propofol and remifentanil before 2 mins during 5 and 15 mins of skull pin fixation were recorded and analyzed
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None