Ignite Creation Date:
2024-05-06 @ 4:53 PM
Last Modification Date:
2024-10-26 @ 2:18 PM
Study NCT ID:
NCT05126732
Status:
UNKNOWN
Last Update Posted:
2021-11-19
First Post:
2021-10-28
Brief Title:
Ganglion Cell Thickness in Enuresis Nocturna
Sponsor:
Izmir Bakircay University
Organization:
Izmir Bakircay University
Study Overview
Official Title:
Is Ganglion Cell Thickness the Main Problem in Enuresis Nocturna
Status:
UNKNOWN
Status Verified Date:
2021-11
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The precise role of the intrinsic circadian regulatory mechanism behind the pathogenesis of enuresis is not fully understood but in theory circadian rhythm irregularity may be the primary pathogenic mechanism not only for urinary outflow mechanisms but also for nocturnal bladder function The proximity between SCN centers that control AVP release sleeparousal voiding and baroreregulation may provide the basis for circadian rhythm disturbance in one or more of these biological functions Ganglion cells containing melanopsin pigment in the retina transmit the information they receive from the outside world about the light-dark state to the SCN via the retinohypothalamic pathway Peripapillary retinal nerve fiber layer RNFL thickness optic nerve head and macula are examined most frequently for the diagnosis of glaucoma and the detection of progression with optical coherence tomography OCT If differences in ganglion cell thickness can be detected using OCT in these children a new avenue in Enuresis Nocturna may be opened
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None