Ignite Creation Date:
2024-05-06 @ 4:48 PM
Last Modification Date:
2024-10-26 @ 2:16 PM
Study NCT ID:
NCT05096585
Status:
COMPLETED
Last Update Posted:
2023-03-10
First Post:
2021-10-14
Brief Title:
Sleep Timing on Energy Intake and Energy Expenditure
Sponsor:
University of Missouri-Columbia
Organization:
University of Missouri-Columbia
Study Overview
Official Title:
Sleep Restriction and Altered Sleep Timing on Energy Intake and Energy Expenditure
Status:
COMPLETED
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Studies in healthy young adults have shown that abnormal and undesirable physiological changes are a result of chronic sleep curtailment with implications on inflammatory status blood glucose regulation circulating free fatty acids and insulin sensitivity Epidemiological studies suggest an increase in energy intake with shortened sleep and this has been associated with weight gain Interestingly most studies examining sleep restriction do not consider whether the restricted sleep is due to sleep delay or an advanced wake time This study will investigate the change in physical activity or food intake during a period of sleep restriction To date only one study has addressed this question but they only examined one study night and followed their subjects for only 24 hr The objective of the proposed project is to examine the effects of shortened sleep on potential changes in physical activity and energy intake
The investigators hypothesize that after several nights of short sleep that different strategies are employed to remain awake and these strategies will also vary whether bed time was delayed or wake time was advanced
Aim 1 To examine the effects of sleep timing on energy intake and expenditure during periods of sleep restriction
The investigators hypothesize that after several nights of short sleep that different strategies are employed to remain awake and these strategies will also vary whether bed time was delayed or wake time was advanced
Aim 1 To examine the effects of sleep timing on energy intake and expenditure during periods of sleep restriction
Detailed Description:
Subjects will have preliminary screening tests There will be 3 study conditions with the latter 2 conditions delayed bed timeadvanced wake time will be completed in a randomized crossover design Subjects will wear an activity monitor actigraph and sleep monitor actiwatch for 6 days Dietary records and smart phones will be used record energy intake
For the first experimental condition the subject will wear the actiwatch and actigraph and monitor food intake for 6 day of normal sleep This condition will allow determination of their sleep pattern and when they habitually go to bed ie 11 pm - 5 am and awaken
On the second condition the investigators will allow subjects to maintain their usual physical activity and dietary patterns but the investigators will ask subjects to delay the time of going to bed by 2 hr Subjects will be followed for 4 nights of shortened sleep but data will be collected for 6 days On the other condition subjects will go to bed at the usual time but awaken 2 hr earlier that they normally would Again subjects will monitor their physical activity hungerfullness sleep and energy intake These latter 2 conditions will be randomized
Visit 1 Subjects will be provided a verbal explanation of the study and will sign the informed consent if interested Subjects will then complete questionnaires assessing health history sleep morningness and physical activity habits
Visit 2 Subjects will collect physical activity monitor actigraph and sleep monitor actiwatch along with surveys to fill out each day about dietary consumption sleep habits and physical activity lasting for 6 days Subjects will also be asked to photograph any food or drink they consume
Visit 3 Return the actiwatch and actigraph
Visit 4-5 Repeat of Visit 2-3
Visit 6-7 Repeat of Visit 2-3
For the first experimental condition the subject will wear the actiwatch and actigraph and monitor food intake for 6 day of normal sleep This condition will allow determination of their sleep pattern and when they habitually go to bed ie 11 pm - 5 am and awaken
On the second condition the investigators will allow subjects to maintain their usual physical activity and dietary patterns but the investigators will ask subjects to delay the time of going to bed by 2 hr Subjects will be followed for 4 nights of shortened sleep but data will be collected for 6 days On the other condition subjects will go to bed at the usual time but awaken 2 hr earlier that they normally would Again subjects will monitor their physical activity hungerfullness sleep and energy intake These latter 2 conditions will be randomized
Visit 1 Subjects will be provided a verbal explanation of the study and will sign the informed consent if interested Subjects will then complete questionnaires assessing health history sleep morningness and physical activity habits
Visit 2 Subjects will collect physical activity monitor actigraph and sleep monitor actiwatch along with surveys to fill out each day about dietary consumption sleep habits and physical activity lasting for 6 days Subjects will also be asked to photograph any food or drink they consume
Visit 3 Return the actiwatch and actigraph
Visit 4-5 Repeat of Visit 2-3
Visit 6-7 Repeat of Visit 2-3
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None