Ignite Creation Date:
2024-05-06 @ 4:47 PM
Last Modification Date:
2024-10-26 @ 2:16 PM
Study NCT ID:
NCT05093023
Status:
COMPLETED
Last Update Posted:
2021-10-26
First Post:
2021-10-13
Brief Title:
ABCB1 SNPs as Predictors of PIPN
Sponsor:
Ain Shams University
Organization:
Ain Shams University
Study Overview
Official Title:
ABCB1 Single Nucleotide Polymorphism Genotypes as Predictors of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer
Status:
COMPLETED
Status Verified Date:
2021-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study aim is to determine the allele frequencies of 1236 GA and 3435 GA in ABCB1 and study their association with the incidence and severity of paclitaxel-induced peripheral neuropathy while adjusting for other baseline covariates in Egyptian patients Additionally the study aimed at fitting and validating logistic regression models with the aforementioned SNPs evaluated in additive dominant overdominant and recessive genetic models and performing diagnostics for the best model in terms of internal validity
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None