Ignite Creation Date:
2024-05-06 @ 4:46 PM
Last Modification Date:
2024-10-26 @ 2:16 PM
Study NCT ID:
NCT05088811
Status:
UNKNOWN
Last Update Posted:
2021-10-22
First Post:
2021-08-21
Brief Title:
The Role of Long Non-coding RNAs WRAP53 and UCA-1 as Potential Biomarkers in Diagnosis of Hepatocellular Carcinoma
Sponsor:
Alexandria University
Organization:
Alexandria University
Study Overview
Official Title:
The Role of Long Non-coding RNAs WRAP53 and UCA-1 as Potential Biomarkers in Diagnosis of Hepatocellular Carcinoma
Status:
UNKNOWN
Status Verified Date:
2021-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this work is to study the role of long non-coding RNAs WRAP53 and urothelial carcinoma-associated 1 UCA1 as potential biomarkers in diagnosis of hepatocellular carcinoma
Detailed Description:
Sample size calculation was done in department of medical statistics Medical Research Institute Alexandria University and the total minimal sample size was calculated
A prospective case control study will be conducted on 80 subjects divided into three groups
Group 1 Thirty patients having liver cirrhosis and hepatocellular carcinoma diagnosed by tripahsic CT
Group 2 Thirty liver cirrhosis patients without hepatocellular carcinoma diagnosed by abdominal ultrasound examination
Group 3 Twenty normal subjects control group matching in age and sex with patients in groups 1 and 2
Patients will be recruited from the outpatient clinics and inpatient wards of Alexandria Main University Hospital and Medical Research Institute Hospital Full informed consent will be taken from the patients and approval of the ethical committee of the Faculty of Medicine will be fulfilled Exclusion criteria Patients with any inflammatory diseases or other malignancies
A prospective case control study will be conducted on 80 subjects divided into three groups
Group 1 Thirty patients having liver cirrhosis and hepatocellular carcinoma diagnosed by tripahsic CT
Group 2 Thirty liver cirrhosis patients without hepatocellular carcinoma diagnosed by abdominal ultrasound examination
Group 3 Twenty normal subjects control group matching in age and sex with patients in groups 1 and 2
Patients will be recruited from the outpatient clinics and inpatient wards of Alexandria Main University Hospital and Medical Research Institute Hospital Full informed consent will be taken from the patients and approval of the ethical committee of the Faculty of Medicine will be fulfilled Exclusion criteria Patients with any inflammatory diseases or other malignancies
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None