Ignite Creation Date:
2024-05-05 @ 5:27 PM
Last Modification Date:
2024-10-26 @ 9:32 AM
Study NCT ID:
NCT00466401
Status:
COMPLETED
Last Update Posted:
2013-02-20
First Post:
2007-04-25
Brief Title:
Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidation
Sponsor:
Ziv Hospital
Organization:
Ziv Hospital
Study Overview
Official Title:
Phase 4 Study on Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidation In Hypercholesterolemic Patients on Simvastatin
Status:
COMPLETED
Status Verified Date:
2013-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of our study is to Estimate the reduction of LDL by ezetimibe in hypercholesterolemic patients on simvastatinInvestigate the effect of LDL lowering by ezetimibe on platelet activity and LDL tendency to peroxidation in hypercholesterolemic patients on simvastatin therapy
The hypothesis is that
1 LDL lowering by ezetimibe on-top of simvastatin in patients on fixed dose of simvastatin can reduce platelet aggregation due to the potential decreasing of cholesterol content in the platelet membranes
2 LDL lowering by ezetimibe can lower LDL tendency to peroxidation
The hypothesis is that
1 LDL lowering by ezetimibe on-top of simvastatin in patients on fixed dose of simvastatin can reduce platelet aggregation due to the potential decreasing of cholesterol content in the platelet membranes
2 LDL lowering by ezetimibe can lower LDL tendency to peroxidation
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None