Ignite Creation Date:
2024-05-06 @ 4:38 PM
Last Modification Date:
2024-10-26 @ 2:13 PM
Study NCT ID:
NCT05048511
Status:
WITHDRAWN
Last Update Posted:
2021-09-27
First Post:
2016-05-09
Brief Title:
Impact of Vitamine D Status on in Vitro Fertilization Outcomes
Sponsor:
Nantes University Hospital
Organization:
Nantes University Hospital
Study Overview
Official Title:
Evaluation of the Impact of Vitamine D Status on in Vitro Fertilization Outcomes in a Large Population of Infertile Women
Status:
WITHDRAWN
Status Verified Date:
2021-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
The project was abandoned because of a lot of publications on the subject in the meantime and it was not considered relevant to continue
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DFIV
Brief Summary:
Non skeletal effect of vitamin D have been the focus of much interest in the past decade During the last years special attention has been given to the impact of vitamin D on human reproduction Its receptor is expressed in most reproductive organs including hypothalamus pituitary gland uterus ovary mammary gland and the placenta In vitro experiments suggest that vitamin D would be involved in regulated embryo-implantation Concerning AMH vitamin D seems to alters AMH signaling in human granulosa cells although their circulated levels are correlated in lated reproductive aged women The results of precedents studies about the impact of vitamin D on IVF outcomes remain conflicting The aim of our study was to assess in a large unselected population of infertile women the impact of vitamin D deficiency on IVF outcome and to examine the relationship between serum vitamin D levels and the ovarian reserve marker AMH
Detailed Description:
Vitamin D was measured on the sixth day of stimulation According to vitamin D level women were divided into 2 groups deficiency when 25OHD 20 ngml and sufficient when 25OHD 20 ngml
Pregnancy rates were compared among these two groups after controlling age BMI characteristics of ovarian stimulation number of ovocytes obtains etc
Pregnancy rates were compared among these two groups after controlling age BMI characteristics of ovarian stimulation number of ovocytes obtains etc
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None