Ignite Creation Date:
2024-05-05 @ 5:27 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00453700
Status:
COMPLETED
Last Update Posted:
2019-03-13
First Post:
2007-03-28
Brief Title:
Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on Electrocardiogram
Sponsor:
Olive View-UCLA Education Research Institute
Organization:
Olive View-UCLA Education Research Institute
Study Overview
Official Title:
Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on Electrocardiogram
Status:
COMPLETED
Status Verified Date:
2007-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Chagas disease is endemic to the Americas infecting between 16-18 million individuals In immigrant populations in the United States from endemic areas it is estimated up to 49 may be asymptomatic carriers of Trypanosoma cruzi the organism which causes Chagas disease Between 10-20 of these patients progress to development of end-stage cardiomyopathy with a high associated morbidity Following acute disease patients enter into an indeterminate phase which can last 10-20 years The earliest sign of cardiac involvement usually is electrocardiogram abnormalities The most common abnormality is right bundle branch block RBBB followed by left anterior fascicular block LAFB and left bundle branch block LBBB Recent studies have shown that treatment of patients at this stage with antiparasitics may delay the progression of overt cardiomyopathy
At the University of California Los Angeles there is a large population of immigrant patients from countries endemic to Chagas disease The researchers propose that screening patients with conduction abnormalities on electrocardiogram may be a potentially useful method to identify patients with early cardiac manifestations of Chagas disease The researchers hope to enroll approximately 300 individuals with RBBB LAFB or LBBB on electrocardiogram to determine the incidence of Chagas disease in this patient population
At the University of California Los Angeles there is a large population of immigrant patients from countries endemic to Chagas disease The researchers propose that screening patients with conduction abnormalities on electrocardiogram may be a potentially useful method to identify patients with early cardiac manifestations of Chagas disease The researchers hope to enroll approximately 300 individuals with RBBB LAFB or LBBB on electrocardiogram to determine the incidence of Chagas disease in this patient population
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None