Ignite Creation Date:
2024-05-06 @ 4:35 PM
Last Modification Date:
2024-10-26 @ 2:12 PM
Study NCT ID:
NCT05031065
Status:
RECRUITING
Last Update Posted:
2024-06-24
First Post:
2021-08-25
Brief Title:
Prognostic Indicators for Radiation-induced Breast Fibrosis
Sponsor:
AHS Cancer Control Alberta
Organization:
AHS Cancer Control Alberta
Study Overview
Official Title:
Identifying Prognostic Indicators for the Development of Radiation-induced Breast Fibrosis
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To study the inflammatory response during and after radiotherapy especially by measuring the concentration of an enzyme called autotaxin and its product LPA in the blood plasma
Detailed Description:
To study the inflammatory response during and after radiotherapy especially by measuring the concentration of an enzyme called autotaxin and its product LPA in the blood plasma Autotaxin and LPA cause fibrosis in other situation but they have not been tested in radiation-induced fibrosis We will determine if the duration and magnitude of the autotaxin and LPA responses are prognostic for the 15-28 of patients who will develop fibrosis This fibrosis will be detected by ultrasound and a novel application of elastography which should provide much earlier and quantifiable fibrotic changes compared to conventional physical examination
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None