Ignite Creation Date:
2024-05-05 @ 5:26 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00450151
Status:
COMPLETED
Last Update Posted:
2012-03-01
First Post:
2007-03-20
Brief Title:
Platelet Activation Markers in Pediatric Cardiac Surgery
Sponsor:
Weill Medical College of Cornell University
Organization:
Weill Medical College of Cornell University
Study Overview
Official Title:
Effect of Cardiopulmonary Bypass on Platelet Activation Markers Such as Platelet Factor 4 and Transforming Growth Factor B in Pediatric Cardiac Surgery
Status:
COMPLETED
Status Verified Date:
2012-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study the focus will be on correlating the levels of platelet activation markers proteins that are released when blood cells are activatedto the duration of cardiopulmonary bypass temperature during cardiopulmonary bypass and the weight of the patient
Detailed Description:
This research is being done because we would like to learn more about platelet dysfunction in children undergoing cardiopulmonary bypass
It has been an established fact that cardiopulmonary bypass causes dysfunction in platelets Activation of platelets during cardiopulmonary bypass is implicated as being a major factor in causing platelet dysfunction
For all participants approximately 315 ml of blood will be collected in special tubes called CTAD tubes before and after cardiopulmonary bypass 630ml in total This amount of blood draw is well within the guidelines of NIH National Institute of Health
Enzyme-linked immunosorbent assay ELISA will be performed using this plasma to make quantitative assessment of Platelet factor 4 and Transforming growth factor beta
It has been an established fact that cardiopulmonary bypass causes dysfunction in platelets Activation of platelets during cardiopulmonary bypass is implicated as being a major factor in causing platelet dysfunction
For all participants approximately 315 ml of blood will be collected in special tubes called CTAD tubes before and after cardiopulmonary bypass 630ml in total This amount of blood draw is well within the guidelines of NIH National Institute of Health
Enzyme-linked immunosorbent assay ELISA will be performed using this plasma to make quantitative assessment of Platelet factor 4 and Transforming growth factor beta
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None