Ignite Creation Date:
2024-05-05 @ 5:26 PM
Last Modification Date:
2024-10-26 @ 9:32 AM
Study NCT ID:
NCT00459329
Status:
UNKNOWN
Last Update Posted:
2008-06-04
First Post:
2007-04-09
Brief Title:
PEARL Intervention to Reduce Depression Among Adults With Epilepsy
Sponsor:
University of Washington
Organization:
University of Washington
Study Overview
Official Title:
PEARL Intervention to Reduce Depression Among Adults With Epilepsy
Status:
UNKNOWN
Status Verified Date:
2008-06
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PEARL
Brief Summary:
The purpose of this study is to test the effectiveness of a home-based depression treatment intervention called Program to Encourage Active Rewarding Lives PEARL We hypothesize that over a 12-month period compared to usual care those receiving the PEARL intervention will show more improvement with their depression have higher quality of life and function and use fewer medical services
Detailed Description:
Compared to non-depressed individuals with epilepsy those with depression have significantly higher rates of suicide lower social and occupational functioning decreased quality of life independent of seizure frequency and higher non-psychiatric health care utilization Adults with epilepsy are more likely to be homebound as a result of reduced function and restrictions in driving opportunities to obtain enhanced quality of care for depression may be limited This study tests the effectiveness of a home-based multi-modal depression treatment intervention called Program to Encourage Active Rewarding Lives PEARL PEARL consists of problem solving treatment social and physical activation pleasant events scheduling support and education regarding antidepressant medication use as well as psychiatric consultation and recommendations regarding initiation or adjustment of antidepressant medications
In a sample of adults with epilepsy who have minor depression major depression andor dysthymia we hypothesize that over a 12-month period compared to usual care those randomized to the PEARL intervention will achieve higher levels of depression response and remission achieve higher quality of life and function and utilize less non-psychiatric health care
By providing a multi-modal home-based stepped collaborative care intervention for adults with depression and epilepsy this program will offer practical alternatives to usual care and will provide a program for improving depression outcomes quality of life and potentially epilepsy outcomes
In a sample of adults with epilepsy who have minor depression major depression andor dysthymia we hypothesize that over a 12-month period compared to usual care those randomized to the PEARL intervention will achieve higher levels of depression response and remission achieve higher quality of life and function and utilize less non-psychiatric health care
By providing a multi-modal home-based stepped collaborative care intervention for adults with depression and epilepsy this program will offer practical alternatives to usual care and will provide a program for improving depression outcomes quality of life and potentially epilepsy outcomes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| SIP 07-2006 | None | None | None |
| NCT00459329 | None | None | None |