Viewing Study NCT00454311



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Study NCT ID: NCT00454311
Status: COMPLETED
Last Update Posted: 2011-03-04
First Post: 2007-03-29

Brief Title: The Impact of the Biopsy of 1-2 Cells in a PGD Program for Anueploidy Screening
Sponsor: Instituto Valenciano de Infertilidad IVI VALENCIA
Organization: Instituto Valenciano de Infertilidad IVI VALENCIA

Study Overview

Official Title: Prospective and Randomized Study of the Impact of the Biopsy of 1-2 Cells in a PGD Program for Aneuploidy Screening
Status: COMPLETED
Status Verified Date: 2011-03
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The aim of this study is to evaluate the impact of the biopsy of one or two cells in a preimplantatation genetic diagnosis program PGD for the screening of aneuploidies This prospective and randomized study will be performed at the Instituto Valenciano de Infertilidad in Valencia Spain in those patientes included in our clinical program Our purpose is to optimize the methodology employed in our laboratory in order to guarantee optimal implantation and pregnancy rates without a detrimental effect on the accuracy and efficiency of the cytogenetic analysis Patients will undergo and IVF cycle embryo biopsy will be performed on day 3 embryos in two fashions in some patients only one cell per embryo will be retrieved whereas in others 2 cells will be retrieved in good morphology embryos and only 1 in the slowl ones In all cases aneuploidy screening will be performed by FISH for chromosomes 13 16 18 21 22 X and Y Embryo developmente will be checked every 24 hours and chormosomally normal embryos will be replaced into the uterus on day 5 of development
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None