Ignite Creation Date:
2024-05-06 @ 4:23 PM
Last Modification Date:
2024-10-26 @ 2:09 PM
Study NCT ID:
NCT04966494
Status:
COMPLETED
Last Update Posted:
2021-07-19
First Post:
2021-07-02
Brief Title:
Impact of Beans and Oats Snack Bar on Hypertriglyceridemic Women
Sponsor:
Universidad Autonoma de Queretaro
Organization:
Universidad Autonoma de Queretaro
Study Overview
Official Title:
Effect of the Consumption of a Common Bean Phaseolus Vulgaris L and Oats Snack Bar on the Proteomic Profile of Human Mononuclear Cells
Status:
COMPLETED
Status Verified Date:
2021-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hypertriglyceridemia is a serious condition in the Mexican population and it is considered a major risk factor for cardiovascular disease Current efforts to prevent dyslipidemia and lipids alteration include the development of functional products as an alternative for the management of hypertriglyceridemia Common beans Phaseolus vulgaris L are a recognized good source of bioactive compounds mainly phenolic compounds total dietary fiber insoluble and soluble fiber resistant starch and oligosaccharides saponins and phytosterols that exert hypolipidemic effects In this sense the development of beans-based food products is an alternative for improving the general health status In previous work a beans-oats snack bar formulation was found to be a promising potential functional product In order to validate those results the aim of this works was to assess a clinical trial was conducted with Mexican women to assess the effect of daily consumption of the functional product on serum triglycerides and certain plasma proteins involved in lipids metabolism in a clinical trial The clinical trial was 2 months randomized parallel study where 32 women with elevated triglycerides were randomized into the treatment group and control group The Control group received nutritional orientation whereas the treatment group received the orientation and consumed 50 g of the product per day Fasting blood samples were collected at baseline and the end of the study obtaining serum and plasma for analysis of lipids profile glucose and biomarkers To determine changes in plasma proteins a 182 protein Human Obesity Antibody Array was used and the results were analyzed using a bioinformatic-based analysis from Ingenuity Pathways Analysis QIAGEN
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None