Ignite Creation Date:
2024-05-05 @ 5:25 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00451529
Status:
UNKNOWN
Last Update Posted:
2011-04-19
First Post:
2007-03-22
Brief Title:
Predictive Value for Stroke
Sponsor:
Dutch Heart Foundation
Organization:
Dutch Heart Foundation
Study Overview
Official Title:
Predictive Value of Magnetic Resonance Imaging MRI 18-Fluorodeoxyglucose Positron Emission Tomography FDG-PET and Microemboli Detection for Stroke
Status:
UNKNOWN
Status Verified Date:
2011-04
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with a moderate to severe carotid atherosclerotic plaque are at risk for stroke and this risk increases with increasing degree of stenosis It has been shown that carotid endarterectomy in symptomatic patients with a carotid artery stenosis of 70-99 is highly beneficial However the beneficial effect of surgery in patients with symptomatic 30-69 stenosis is not clear yetA clear beneficial effect of surgery in the 30-69 stenosis group might be found in a sub-group of patients whom are at greater risk for stroke Definition of this sub-group might be achieved by plaque characterization since rupture of a vulnerable plaque is the main cause of stroke due to carotid artery stenosisThis study will include patients with a 30-69 carotid artery stenosis and assess plaque composition by MRI the degree of plaque inflammation by FDG-PET and the amount of microembolization by transcranial Doppler ultrasound The main purpose of this study is to assess whether one or a combination of each of these imaging methods can predict the occurrence of a recurrent ischemic stroke
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None