Viewing Study NCT04955782



Ignite Creation Date: 2024-05-06 @ 4:21 PM
Last Modification Date: 2024-10-26 @ 2:08 PM
Study NCT ID: NCT04955782
Status: UNKNOWN
Last Update Posted: 2021-09-22
First Post: 2021-07-05

Brief Title: Abstinence Period and Semen Quality
Sponsor: ART Fertility Clinics LLC
Organization: ART Fertility Clinics LLC

Study Overview

Official Title: Abstinence Period and Semen Quality
Status: UNKNOWN
Status Verified Date: 2021-09
Last Known Status: RECRUITING
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Does period of abstinence impact progressive motility in oligoasthenoteratozoospermic OATS males In the evaluation of male fertility semen analysis is an important investigation An abstinence between 2 and 7 days before a diagnostic semen analysis has been recommended by WHO WHO 2010 guidelines for the sake of standardization The European Society of Human Reproduction and Embryology advises 3-4 days of abstinence before a semen analysis The exact impact of abstinence period on sperm quality is a little complex and difficult to interpret This study 250 men with low sperm counts motility and morphology will be recruited The results will be analyzed to ascertain the impact of shorter abstinence period on semen quality
Detailed Description: The population will be the citizens and residents of Oman All men included in the study will be the ones diagnosed in the last one year with oligoasthenoteratozoospermia There are multiple factors that affect the semen parameters in assisted reproductive procedures One of the factors is period of abstinence It has been observed that prolonged abstinence improves semen volume and sperm concentration but it may have a negative impact on sperm viability and motility The present abstinence guidelines are for testing and analysis only however it is possible that varying periods of abstinence may lead to higher clinical pregnancies

If sufficient sample has not been accomplished even after considering non-response investigators will optimize sampled data with complete information required for research Regression imputation statistical technique will be done Instead of deleting any case that has any missing value this approach preserves all cases by replacing the missing data with a probable value estimated by remaining information The existing variables are used to make a prediction and then the predicted value is substituted as if an actual obtained value After all missing values will be replaced the complete data set will be analyzed using the above mentioned standard techniques to meet the objectives

The data collected will be stored in a password coded excel sheet The verification of sample provider will be done by two people Also two embryologists will cross check the identifier details with the sample The anonymity of patient will be maintained by logging the data onto an excel sheet without any name only patient number The sample will be identified based on the Vrepro number which is a unique ID for the patient Eg For patient XID is 0004797 The details will be saved in a sheet with the ID number 4797 only

The data base will be rigorously defined with the variables destined to be analyzed according to the objectives set The necessary information will be exported from the clinical information manager Vrepro to a table in Excel format The exported data will be duly codified in order to protect the clinical and personal information of the patients according to the applicable law in the place where the research project is carried out Finally and prior to the statistical study an exploratory data analysis will be carried out to review the quality of the information extracted

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None