Ignite Creation Date:
2024-05-05 @ 5:24 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00449423
Status:
TERMINATED
Last Update Posted:
2007-10-25
First Post:
2007-03-19
Brief Title:
Metabolic Modulation as Treatment in Acute Heart Failure
Sponsor:
University of Aarhus
Organization:
University of Aarhus
Study Overview
Official Title:
Metabolic Modulation as Treatment in Acute Heart Failure
Status:
TERMINATED
Status Verified Date:
2007-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
due to slow recruitment
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MEMO
Brief Summary:
The primary objective of this study is to evaluate whether metabolic modulation improves hemodynamics and outcome in acute heart failure
Detailed Description:
Acute heart failure is a serious disease that despite modern therapies carries a high mortality Inotropic drugs improve patient status but yield a higher risk of death Previous studies have shown that myocardial contractility improves when glucose fermentation is up regulated and decreases when Free Fatty Acids are high In a placebo-controlled design we wish to shift myocardial substrate metabolism towards increased glucose uptake and utilization and measure hemodynamics and biochemical markers of metabolism and prognosis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None