Ignite Creation Date:
2024-05-06 @ 4:17 PM
Last Modification Date:
2024-10-26 @ 2:07 PM
Study NCT ID:
NCT04936438
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-05-08
First Post:
2021-06-12
Brief Title:
Clinical Cohort Study - INTERCATH
Sponsor:
University of Hamburg-Eppendorf
Organization:
University of Hamburg-Eppendorf
Study Overview
Official Title:
Clinical Cohort Study - INTERCATH A Diseased Cohort Based Epidemiologic Prospective Single Center Cohort Study for Novel Research in Cardiovascular Risk Prediction Using a Sophisticated Biobank
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Within a CAD patient cohort there is a wide variability of clinical manifestation and severity of coronary disease Distinct determinants that would explain the variety of CAD phenotypes with differing prognosis are yet undiscovered Aim of this study is to find genetic variants biomarkers and clinical cardiovascular risk factors that relate to specific coronary artery disease phenotypes and related pathologies in a patient population
Detailed Description:
Atherosclerotic Coronary Artery Disease CAD is one of the leading causes of death in industrialized countries and accounts for a high lifetime prevalence Within a CAD patient cohort there is a broad inter-individual difference with regard to clinical manifestation and severity of disease eg stable angina vs acute coronary syndrome calcified vs thrombotic coronary lesions or one vessel vs complex three vessel disease or left main stenosis Thus depending on the CAD phenotype there is a broad difference in CAD patients prognosis Similarly other non-atherosclerotic coronary pathologies such as Spontaneous Coronary Dissection SCAD are related with devastating illness in mainly young patients For these patients there is an unmet need in the knowledge of epidemiology presentation current management and outcome Aim of this study is to discover genetic variants biomarkers and clinical cardiovascular risk factors that relate to specific CAD and related coronary pathologies phenotypes in a national patient population This may allow an improvement of individualized risk stratification and contribute to discover pathways in the pathogenesis and open the avenue for potential therapeutic targets
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None