Ignite Creation Date:
2025-12-24 @ 12:41 PM
Ignite Modification Date:
2025-12-27 @ 10:16 PM
Study NCT ID:
NCT03494361
Status:
COMPLETED
Last Update Posted:
2020-07-23
First Post:
2018-04-02
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Evaluation of Dysphagia by 6-chnnel Surface Electromyography
Sponsor:
Seoul National University Hospital
Organization:
Study Overview
Official Title:
Evaluation of Dysphagia by 6-chnnel Surface Electromyography and Preliminary Study for Design 6-channel Electrical Stimulation
Status:
COMPLETED
Status Verified Date:
2020-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The natural process of aging affects a few very specific timing parameters such as swallow reaction time and hyoid one movement velocity.
Many swallow timing and bolus transit parameters appear to be unaffected by aging. We want to know the changes of kinematic variables according to the aging process.
First hypothesis: There are probably be a protection mechanism that blocks functional loss progressing to kinematic abnormality. Muscle activation sequence change (i.e duration or amplitude) of the oropharyngeal muscles play an important role.
Second hypothesis: Age-related differences in muscle activation patterns will also appear differently depending on the characteristics of swallowed food.
Many swallow timing and bolus transit parameters appear to be unaffected by aging. We want to know the changes of kinematic variables according to the aging process.
First hypothesis: There are probably be a protection mechanism that blocks functional loss progressing to kinematic abnormality. Muscle activation sequence change (i.e duration or amplitude) of the oropharyngeal muscles play an important role.
Second hypothesis: Age-related differences in muscle activation patterns will also appear differently depending on the characteristics of swallowed food.
Detailed Description:
Inclusion criteria
Inclusion criteria of healthy older adults : Age \> 60, without dysphagia, comorbidity
Inclusion criteria of young control group
: Age \< 60, without dysphagia, comorbidity
No prior history of swallowing difficulty or history of central nervous system disease, and none were taking medication that are known to affect swallowing.
Surface EMG was performed at bilateral suprahyoid, thyrohyoid, sternothyroid and pharyngeal constrictors. The latency of activation and termination was checked.
Inclusion criteria of healthy older adults : Age \> 60, without dysphagia, comorbidity
Inclusion criteria of young control group
: Age \< 60, without dysphagia, comorbidity
No prior history of swallowing difficulty or history of central nervous system disease, and none were taking medication that are known to affect swallowing.
Surface EMG was performed at bilateral suprahyoid, thyrohyoid, sternothyroid and pharyngeal constrictors. The latency of activation and termination was checked.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: