Ignite Creation Date:
2024-05-06 @ 4:15 PM
Last Modification Date:
2024-10-26 @ 2:06 PM
Study NCT ID:
NCT04923477
Status:
RECRUITING
Last Update Posted:
2023-11-09
First Post:
2021-06-06
Brief Title:
Therapeutic Exercise for Rotator Cuff Tendinopathy Subacromial Pain Syndrome - Outcomes and Mechanisms
Sponsor:
University of Southern California
Organization:
University of Southern California
Study Overview
Official Title:
Mechanisms of Exercise for Rotator Cuff Tendinopathy Subacromial Pain Syndrome
Status:
RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Rotator cuff tendinopathy one of the pathologies identified as part of the cluster of shoulder symptoms known as subacromial pain syndrome is a common musculoskeletal shoulder condition Resolution of pain and disability is poor despite treatment with only about 50 reporting full recovery at 12 - 18 months Prior studies suggest therapeutic exercise when used alone and with other interventions can have positive outcomes however not all patients with rotator cuff tendinopathy respond Few studies have assessed the effects of exercise for individuals with chronic pain especially brain driven mechanisms thought to play a key role In this study we will use brain imaging to understand the mechanisms identify predictors of a positive response to exercise and the relationship to biomechanical and pain-related factors in patients with RC tendinopathy The findings from this study will optimize the delivery and treatment response to exercise for individuals with shoulder pain
Detailed Description:
Theoretical models propose the development of shoulder pain from an acute injury or repetitive motion seen in sports and certain work environments Repetitive motions in combination with altered muscle activity and altered movement strategies may lead to damage of the rotator cuff structures resulting in local shoulder pain Emerging evidence supports the hypothesis that localized pain may result in chronic centralized pain over time through central sensitization Central nervous system changes specifically those at the level of the brain have been shown to play a role in chronic pain Neurophysiological mechanisms have been shown to predict symptom progression in other chronic pain conditions Despite a large body of evidence that therapeutic exercise mechanisms leading to pain relief are still not well understood Studies identify a critical role of exercise in modulating excitation and inhibition of key pain centers in the central nervous systems However limited evidence exists as to the mechanisms of exercise in the management of patients with chronic pain with therapeutic exercise
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None