Ignite Creation Date:
2024-05-06 @ 4:15 PM
Last Modification Date:
2024-10-26 @ 2:06 PM
Study NCT ID:
NCT04920994
Status:
COMPLETED
Last Update Posted:
2022-07-11
First Post:
2021-06-03
Brief Title:
Modified Thoracoabdominal Nerve Block Through Perichondrial Approach M-TAPA in Major Abdominal Surgeries
Sponsor:
Sameh Fathy
Organization:
Mansoura University
Study Overview
Official Title:
Modified Thoracoabdominal Nerve Block Through Perichondrial Approach M-TAPA in Comparison to Subcostal Transverse Abdominis Plane Block TAP in Major Abdominal Surgeries
Status:
COMPLETED
Status Verified Date:
2022-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will be conducted to evaluate efficacy of ultrasound guided modified thoracoabdominal nerves block via a new perichondrial approach M-TAPA for postoperative analgesia in major abdominal surgeries in comparison to subcostal transverse abdominis plane SCTAP block
It is hypothesized that M-TAPA block will be advantageous to SCTAP block as a promising effective alternative for analgesia for major abdominal surgeries with fewer side effects
It is hypothesized that M-TAPA block will be advantageous to SCTAP block as a promising effective alternative for analgesia for major abdominal surgeries with fewer side effects
Detailed Description:
Postoperative pain management for major abdominal surgeries can reduce postoperative respiratory dysfunction and promote early mobilization Traditionally opioids have been used to manage postoperative pain However an increasing awareness of opioid-related adverse events including respiratory depression paralytic ileus and sedation has led to a shift towards utilizing opioid-sparing techniques for postoperative analgesia As such outcomes associated with the transverse abdominis plane block are of increasing interest A modified thoracoabdominal nerves block via a new perichondrial approach M-TAPA is a novel analgesic technique that involves local anesthetic injection into the lower aspect of the chondrium It can block thoracoabdominal nerves at T5 in cephalic direction and down to T11-T12 in caudal direction and may be an effective analgesic for major abdominal surgeries
The aim of this study is to assess the quality of pain relief in patients who will undergo major abdominal surgery receiving either M-TAPA block or SCTAP block by comparing and evaluating the differences between the two techniques
This prospective randomized comparative clinical study will include 80 patients who will be scheduled for major abdominal surgery under general anesthesia in Mansoura university hospitals Informed written consent will be obtained from all subjects in the study after ensuring confidentiality Eligible patients will be randomly assigned to 2 equal groups M-TAPA group and SCTAP group according to computer-generated table of random numbers using the permuted block randomization method The collected data will be coded processed and analyzed using SPSS program All data will be considered statistically significant if P value is 005
The aim of this study is to assess the quality of pain relief in patients who will undergo major abdominal surgery receiving either M-TAPA block or SCTAP block by comparing and evaluating the differences between the two techniques
This prospective randomized comparative clinical study will include 80 patients who will be scheduled for major abdominal surgery under general anesthesia in Mansoura university hospitals Informed written consent will be obtained from all subjects in the study after ensuring confidentiality Eligible patients will be randomly assigned to 2 equal groups M-TAPA group and SCTAP group according to computer-generated table of random numbers using the permuted block randomization method The collected data will be coded processed and analyzed using SPSS program All data will be considered statistically significant if P value is 005
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None