Ignite Creation Date:
2024-05-06 @ 4:14 PM
Last Modification Date:
2024-10-26 @ 2:06 PM
Study NCT ID:
NCT04921072
Status:
RECRUITING
Last Update Posted:
2024-03-15
First Post:
2021-06-03
Brief Title:
Neuroplasticity in Motor Learning in Young Adults Under Variable and Constant Practice Conditions
Sponsor:
Masaryk University
Organization:
Masaryk University
Study Overview
Official Title:
Neuroplasticity in Motor Learning Under Variable and Constant Practice Conditions
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NMLPC
Brief Summary:
The project aims at providing a better understanding of motor skill acquisition and learning processes
The primary objectives of the study are to determine how practice conditions ie variable and constant practice conditions in motor learning affect Central Nervous System There are three objectives
1 to determine functional changes following constant and variable practice conditions in motor learning resting-state fMRI
2 to determine the EEG activation and connectivity between cognitive sensory and motor cerebral cortex areas central temporal parietal occipital in constant and variable practice conditions and as a function of practice time
The primary objectives of the study are to determine how practice conditions ie variable and constant practice conditions in motor learning affect Central Nervous System There are three objectives
1 to determine functional changes following constant and variable practice conditions in motor learning resting-state fMRI
2 to determine the EEG activation and connectivity between cognitive sensory and motor cerebral cortex areas central temporal parietal occipital in constant and variable practice conditions and as a function of practice time
Detailed Description:
Variable practice involving the practice of several variations of motor skill benefits learning differently than practice in constant conditions ie practice that involves only one variation of a skill The variable practice results in better retention and transfer The performance of a skill practiced in variable conditions is more accurate and stable In contrast practicing only one variation of a skill better refines the recall schema It means that the motor program which serves as an example while executing a movement is developed better The trained variation of a skill in constant practice produces an advantage in performance compared to the same variation of the skill that was practiced in variable conditions assuming that variable and constant practice had similar capacity
This finding has an important implication for those who want to master their skills and it does not matter whether this skill refers to sport driving piloting or rehabilitation If one wants to be good at performing only one variation of a skill one should practice in constant conditions whereas if one wants to be good in more than one variation of skill and wants to generalize the experience to novel situations an individual should practice in variable conditions As one can see this implication is practical although the mechanisms underlying this distinction and differences are unknown
On the other hand it is unquestioned today that learning new motor skills dynamically changes brain ie brain is neuroplastic The neuroplasticity of the brain is specifically conspicuous in the progression of motor learning As it was reported in previous research cortico-striatal and cortico-cerebellar systems play an important role in motor skill acquisition However both of these systems differ in terms of the role they play as learning progresses Cortico-striatal system associativepremotor brain regions is primarily engaged in the initial phase of learning ie in cognitive functioning and sensory processing Cortico-cerebellar system sensorimotor network is becoming more active in the later phase of motor learning However none of the previous research focused on what role these systems play in learning under different conditions and how the different roles the systems may play affect structural neuroplasticity including grey and white matter
It may be also interesting to look at the functional neuroplasticity A lesser degree of cognitive involvement during the execution of movements may be associated with lower activation in the sensorimotor cortex On the other hand increased cognitive involvement may be expected in variable conditions due to eg stimulus identification or decision making Therefore the assumption that decreased cognitive involvement and as a result decreased prefrontal cortex activation in constant practice conditions sounds reasonable Moreover it may be hypothesized that practicing and learning in constant conditions will be characterized by lower sensorimotor cortex activation since there will be decreased control during the motor performance which leads to more adaptive motor performance
This finding has an important implication for those who want to master their skills and it does not matter whether this skill refers to sport driving piloting or rehabilitation If one wants to be good at performing only one variation of a skill one should practice in constant conditions whereas if one wants to be good in more than one variation of skill and wants to generalize the experience to novel situations an individual should practice in variable conditions As one can see this implication is practical although the mechanisms underlying this distinction and differences are unknown
On the other hand it is unquestioned today that learning new motor skills dynamically changes brain ie brain is neuroplastic The neuroplasticity of the brain is specifically conspicuous in the progression of motor learning As it was reported in previous research cortico-striatal and cortico-cerebellar systems play an important role in motor skill acquisition However both of these systems differ in terms of the role they play as learning progresses Cortico-striatal system associativepremotor brain regions is primarily engaged in the initial phase of learning ie in cognitive functioning and sensory processing Cortico-cerebellar system sensorimotor network is becoming more active in the later phase of motor learning However none of the previous research focused on what role these systems play in learning under different conditions and how the different roles the systems may play affect structural neuroplasticity including grey and white matter
It may be also interesting to look at the functional neuroplasticity A lesser degree of cognitive involvement during the execution of movements may be associated with lower activation in the sensorimotor cortex On the other hand increased cognitive involvement may be expected in variable conditions due to eg stimulus identification or decision making Therefore the assumption that decreased cognitive involvement and as a result decreased prefrontal cortex activation in constant practice conditions sounds reasonable Moreover it may be hypothesized that practicing and learning in constant conditions will be characterized by lower sensorimotor cortex activation since there will be decreased control during the motor performance which leads to more adaptive motor performance
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None