Ignite Creation Date:
2024-05-06 @ 4:14 PM
Last Modification Date:
2024-10-26 @ 2:06 PM
Study NCT ID:
NCT04921033
Status:
RECRUITING
Last Update Posted:
2022-10-18
First Post:
2021-06-04
Brief Title:
Exclusive Enteral Nutrition in Patients With Ileocaecal Crohns Disease
Sponsor:
Duzce University
Organization:
Duzce University
Study Overview
Official Title:
Exclusive Enteral Nutrition in Patients With Ileocaecal Crohns Disease XENIC an Open-label Multicenter Prospective Randomized Clinical Trial
Status:
RECRUITING
Status Verified Date:
2022-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Inflammatory bowel diseases are chronic and progressive entities triggered by exposure to environmental factors in individuals with a genetic background
One of the most common environmental factors is the type of diet which is a key influencer on pathogenesis Nutrients alter the intestinal microbiota thus changing the intestinal permeability The Western-type diet encompasses sugar fat and protein-rich products that have some deleterious effects on the intestinal microbiome compared to the plant-based Mediterranean-type diet
Based on this fact diet-based therapeutic efforts have been used extensively in pediatric Crohns disease patients and there is strong evidence that exclusive enteral nutrition EEN is as effective as corticosteroids to induce both clinical and endoscopic remission but this treatment strategy is underutilized in adults
One of the most common environmental factors is the type of diet which is a key influencer on pathogenesis Nutrients alter the intestinal microbiota thus changing the intestinal permeability The Western-type diet encompasses sugar fat and protein-rich products that have some deleterious effects on the intestinal microbiome compared to the plant-based Mediterranean-type diet
Based on this fact diet-based therapeutic efforts have been used extensively in pediatric Crohns disease patients and there is strong evidence that exclusive enteral nutrition EEN is as effective as corticosteroids to induce both clinical and endoscopic remission but this treatment strategy is underutilized in adults
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None