Ignite Creation Date:
2024-05-05 @ 5:23 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00449306
Status:
UNKNOWN
Last Update Posted:
2019-07-05
First Post:
2007-03-19
Brief Title:
PhysicalHistologicaland Genetic Analyses of Lipid-rich Atherosclerotic Plaques
Sponsor:
Sheba Medical Center
Organization:
Sheba Medical Center
Study Overview
Official Title:
PhysicalHistologicaland Genetic Analyses of Lipid-rich Atherosclerotic Plaques
Status:
UNKNOWN
Status Verified Date:
2019-07
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Lipid-rich atherosclerotic plaques or vulnerable plaques are prone to rupture causing local intravascular thrombosis with subsequent grave clinical consequences Atherosclerotic plaques normally removed during surgery and peripheral blood samples will be studied to achieve the following objectives
1 Define histological features of the vulnerable plaque analyze its physical characteristics and investigate selected gene expression
2 Study biomarkers of inflammation in conjunction with the presence of vulnerable plaques
3 Explore the potential role of infection in atherogenesis
1 Define histological features of the vulnerable plaque analyze its physical characteristics and investigate selected gene expression
2 Study biomarkers of inflammation in conjunction with the presence of vulnerable plaques
3 Explore the potential role of infection in atherogenesis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None