Ignite Creation Date:
2024-05-06 @ 4:12 PM
Last Modification Date:
2024-10-26 @ 2:05 PM
Study NCT ID:
NCT04905186
Status:
COMPLETED
Last Update Posted:
2022-06-14
First Post:
2021-05-13
Brief Title:
Different Domains of Executive Function Dual Task Walking on Brain Activation and Gait Performance in Healthy Adults
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
The Effects of Different Domains of Executive Function Dual Task Walking on Brain Activation and Gait Performance in Healthy Adults
Status:
COMPLETED
Status Verified Date:
2022-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate the effects of different domains of executive function EF during dual task walking condition on brain activation and gait performance in healthy adults There are two experiments will be conducted in this study Experiment 1 is a pilot study to determine the same level of difficulty in 3 EF domains including inhibition working memory and cognitive flexibility Experiment 2 is carried out to investigate the effects of 3 different domains of EF which difficulties are controlled on gait performance and brain activation in dual task condition 10 subjects will perform Stroop test 2s3s4s to change question backward digit spans 345 digits and naming test in Experiment 1 In Experiment 1 the primary outcome is the correct response speed CRS while secondary outcome will be the brain activity In Experiment 2 30 subjects will perform the single cognitive task A SCTA Stroop test single cognitive task B SCTB backward digit spans single cognitive task C SCTC naming test single walking task SWT dual task A DTA walking while performing cognitive task A dual task B DTB walking while performing cognitive task B and dual task C DTC walking while performing cognitive task C The CRS gait performance brain activity and the dual task costs DTC will be recorded in the Experiment 2 Brain activities in prefrontal cortex PFC premotor cortex PMC and supplementary motor area SMAs will be measured by functional near-infrared spectroscopy fNIRS during this study One-way ANOVA with Tukey post-hoc test will be performed to establish the effect of different type of executive task on CRS or the brain activity The differences of gait parameters and brain activity in different condition in the Experiment 2 will be examined by one-way ANOVA with repeated measured Furthermore the Pearson correlation coefficient will be used to examine the correlation of brain activation and executive function performance or gait parameters
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None