Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001584
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Determination of HIV-1 Production by the Prostate
Sponsor:
National Cancer Institute NCI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Determination of HIV-1 Production by the Prostate
Status:
COMPLETED
Status Verified Date:
2000-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Virus present in semen likely contributes substantially to the sexual transmission of HIV However the source of HIV in semen is unknown Some evidence suggests that the prostate may be the source of at least some of the virus in semen This study is designed to determine whether the prostate may serve as the source of virus in semen by comparing the concentration of HIV-1 RNA in semen donated normally in semen obtained following prostatic massage and in expressed prostatic secretions Finding a source for semen HIV would provide important insights into several aspects of HIV sexual transmission Since some drugs do not enter the prostate well the finding that virus is produced in the prostate might suggest the prostate could serve as a reservoir for HIV leading to the development of resistance to antiviral agents
Detailed Description:
Virus present in semen likely contributes substantially to the sexual transmission of HIV However the source of HIV in semen is unknown Some evidence suggests that the prostate may be the source of at least some of the virus in semen This study is designed to determine whether the prostate may serve as the source of virus in semen by comparing the concentration of HIV-1 RNA in semen donated normally in semen obtained following prostatic massage and in expressed prostatic secretions Finding a source for semen HIV would provide important insights into several aspects of HIV sexual transmission Since some drugs do not enter the prostate well the finding that virus is produced in the prostate might suggest the prostate could serve as a reservoir for HIV leading to the development of resistance to antiviral agents
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 97-C-0158 | None | None | None |