Ignite Creation Date:
2024-05-05 @ 5:23 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00442195
Status:
RECRUITING
Last Update Posted:
2024-07-01
First Post:
2007-02-28
Brief Title:
Collection and Analysis of Blood Bone Marrow and Buccal Mucosa Samples From Healthy Volunteers
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Procurement and Analysis of Blood Bone Marrow and Buccal Mucosa Samples From Healthy Volunteers to Support Clinical and Translational Research Projects in the NHLBI
Status:
RECRUITING
Status Verified Date:
2024-05-15
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The Hematology Branch of the National Heart Lung and Blood Institute is doing a variety of laboratory research experiments that require blood and tissue samples from healthy volunteers This protocol provides a mechanism for collecting these tissue samples Research includes studies of normal and abnormal formation of blood cells viral blood diseases the role of the immune system in marrow failure and genetic risk factors for aplastic anemia
Healthy normal volunteers 8 years of age and older may be eligible for this study Samples are collected as follows
Blood samples Participants 8 years of age and older donate up to 4 tablespoons of blood which is obtained from a needle placed in an arm vein
Participants 8 years of age and older donate a buccal mucosa sample cells from the inside of the cheek The inside of the cheek is scraped gently with a nylon brush
Participants 18 years of age and older donate a bone marrow sample The bone marrow is obtained from the hip bone The skin over the area is wiped clean with alcohol and iodine and then a local anesthetic is injected under the skin and also into the bone When the area is numb a bone marrow aspiration needle is introduced through the bone surface into the marrow The marrow cells are collected using a syringe connected to the needle
Healthy normal volunteers 8 years of age and older may be eligible for this study Samples are collected as follows
Blood samples Participants 8 years of age and older donate up to 4 tablespoons of blood which is obtained from a needle placed in an arm vein
Participants 8 years of age and older donate a buccal mucosa sample cells from the inside of the cheek The inside of the cheek is scraped gently with a nylon brush
Participants 18 years of age and older donate a bone marrow sample The bone marrow is obtained from the hip bone The skin over the area is wiped clean with alcohol and iodine and then a local anesthetic is injected under the skin and also into the bone When the area is numb a bone marrow aspiration needle is introduced through the bone surface into the marrow The marrow cells are collected using a syringe connected to the needle
Detailed Description:
The purpose of this protocol is to collect and analyze blood ages 8 and older bone marrow ages 18 and older skin tissue samples ages 18 and older andor buccal mucosa samples ages 8 and older from healthy volunteers Samples will be used for clinical and translational research in the NHLBI and are indispensable for many of our research projects including studies of normal and abnormal hematopoiesis the viral etiology of blood diseases the role of the immune system in marrow failure and genetic risk factors for aplastic anemia This protocol provides a mechanism for collection tracking storing dispensing analyzing and disposing of these laboratory research samples
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 07-H-0113 | None | None | None |