Ignite Creation Date:
2024-05-06 @ 4:11 PM
Last Modification Date:
2024-10-26 @ 2:05 PM
Study NCT ID:
NCT04897815
Status:
UNKNOWN
Last Update Posted:
2021-06-16
First Post:
2021-05-20
Brief Title:
Fasting and Postprandial Cerebral Blood Flow in Type 2 Diabetic Patients
Sponsor:
Qianfoshan Hospital
Organization:
Qianfoshan Hospital
Study Overview
Official Title:
Fasting and Postprandial Cerebral Blood Flow in Type 2 Diabetic Patients
Status:
UNKNOWN
Status Verified Date:
2021-06
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to explore the changes of fasting and postprandial cerebral blood flow in patients with type 2 diabetes mellitus Some studies have proved that non-fasting blood glucose concentration is an independent predictor of ischemic stroke and lacunar infarction At present there are differences in cerebral blood flow velocity between diabetic patients and healthy controls Therefore it is of certain significance to explore the changes of fasting and postprandial cerebral blood flow in patients with type 2 diabetes mellitus
Detailed Description:
In China due to the aging population and the increase in obesity the incidence of diabetes is on the rise Diabetes is the main independent risk factor for cerebrovascular diseases especially ischemic stroke Some studies have proved that non-fasting blood glucose concentration is an independent predictor of ischemic stroke and lacunar infarction Transcranial Doppler TCD can evaluate intracranial blood flow patterns real-time and reliably and provide information about cerebral hemodynamics cerebrovascular reactivity and various pathological changes At present there are some differences in the study of cerebral blood flow velocity in diabetic patients The purpose of our study is to determine the changes of cerebral blood flow on an empty stomach and 1 hour after meal in patients with type 2 diabetes In this study 20 patients with type 2 diabetes mellitus will be selected as the experimental group 20 healthy volunteers whose sex and age and BMI matched with the experimental group will be selected as the control group Fasting blood glucose and TCD will be measured in the two groups and the data of mean flow velocity Vm Goslings pulsatility index PI and cerebrovascular reactivity of cerebral artery will be obtained One hour after drinking 300ml lukewarm water which has dissolved 75g glucose powder the blood glucose will be detected again and TCD examination will be performed again Finally the data will be collected for statistical analysis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None