Viewing Study NCT04897711



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Last Modification Date: 2024-10-26 @ 2:05 PM
Study NCT ID: NCT04897711
Status: COMPLETED
Last Update Posted: 2023-08-14
First Post: 2021-05-10

Brief Title: Perceptual Training to Improve Listeners Ability to Understand Speech Produced by Individuals With Dysarthria
Sponsor: Utah State University
Organization: Utah State University

Study Overview

Official Title: Perceptual Training for Improved Intelligibility of Dysarthric Speech
Status: COMPLETED
Status Verified Date: 2024-09
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: There exist very few effective treatments that ease the intelligibility burden of dysarthria Perceptual training offers a promising avenue for improving intelligibility of dysarthric speech by offsetting the communicative burden from the speaker with dysarthria on to their primary communication partners-family friends and caregivers This project utilizing advanced explanatory models will permit identification of speaker and listener parameters and their interactions that allow perceptual training paradigms to be optimized for intelligibility outcomes in dysarthria rehabilitation This work addresses this critical gap in clinical practice and sets the stage for extension of dysarthria management to listener-targeted remediation-advancing clinical practice and enhanced communication and quality of life outcomes for this population
Detailed Description: There exist very few effective treatments that ease the intelligibility burden of dysarthria and all of these require cognitive and physical effort on the part of the speaker to achieve and maintain gains Therefore individuals with intelligibility deficits whose cognitive and physical impairments limit their ability to modify their speech are currently not viable treatment candidates This constitutes a significant health disparity that disproportionately affects those clinical populations with developmental cognitive andor significant neuromuscular impairment

To address this critical gap in current dysarthria management the weight of behavioral change is shifted from the speaker to the listener While a novel concept for dysarthria management the idea is firmly rooted in the field of psycholinguistics and supported by a programmatic body of research showing that listener-targeted perceptual training paradigms wherein listeners are familiarized with the degraded speech signal and provided with an orthographic transcription of what the speaker is saying result in statistically and clinically significant intelligibility gains in dysarthria Further preliminary evidence suggests that these intelligibility outcomes may be influenced by hypothesis-driven speaker parameters such as acoustic predictability of speech rhythm cues and listener parameters such as expertise in rhythm perception

A requisite next step to bringing listener-targeted perceptual training closer to clinical implementation and the overarching goal of this clinical trial is the systematic and rigorous analysis of the speaker and listener parameters and their interactions that modulate and in some cases optimize perceptual training benefits of intelligibility improvement To achieve this aim an existing database of dysarthric speech 20 speakers with dysarthria and a large cohort of listeners n 400 across two well-established testing sites Utah State University and Florida State University are utilized Thus the key deliverable resulting from this work will be explanatory models that account for the unique and joint contributions of speaker and listener parameters on the magnitude of intelligibility improvement following perceptual training with dysarthric speech

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
R21DC018867 NIH None httpsreporternihgovquickSearchR21DC018867