Ignite Creation Date:
2024-05-06 @ 4:08 PM
Last Modification Date:
2024-10-26 @ 2:04 PM
Study NCT ID:
NCT04880122
Status:
COMPLETED
Last Update Posted:
2021-05-10
First Post:
2021-05-05
Brief Title:
Dried Blood Spots for SARS-CoV-2 Serology COVID-19
Sponsor:
University Ghent
Organization:
University Ghent
Study Overview
Official Title:
Comparison of Dried Blood Spots and Venous Blood for the Detection of SARS-CoV-2 2 Antibodies in a Population of Nursing Home Residents
Status:
COMPLETED
Status Verified Date:
2021-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to validate dried blood spots DBS for SARS-CoV-2 Severe Acute Respiratory Syndrome 2 antibody detection in elderly individuals
Detailed Description:
In the current SARS-CoV-2 pandemic testing for SARS-CoV-2 specific antibodies is paramount to monitor immune responses in post-authorization vaccination and sero-epidemiology studies However large scale and iterative serological testing by venipuncture in older persons can be challenging Capillary blood sampled using a finger prick and collected on protein saver cards ie dried blood spots DBS has already proven to be a promising alternative However elderly persons have a reduced cutaneous microvasculature which may affect DBS-based antibody testing Therefore we aimed to evaluate the performance of DBS for the detection of SARS-CoV-2 antibodies in nursing homes residents We collected venous blood and paired Whatman and EUROIMMUN DBS from nursing home residents and from staff as a reference population Venous blood samples were analyzed for the presence of SARS-CoV-2 IgG antibodies using the Abbot chemiluminescent microparticle immunoassay CMIA DBS were analyzed by the EUROIMMUN enzyme-linked immuno sorbent assay ELISA for SARS-CoV-2 IgG antibodies
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None