Ignite Creation Date:
2024-05-06 @ 4:08 PM
Last Modification Date:
2024-10-26 @ 2:04 PM
Study NCT ID:
NCT04888637
Status:
COMPLETED
Last Update Posted:
2022-10-17
First Post:
2021-05-11
Brief Title:
Pediatric Language and Memory Mapping in Refractory Epilepsy Using Magnetoencephalography
Sponsor:
University of Arkansas
Organization:
University of Arkansas
Study Overview
Official Title:
Pediatric Language and Memory Mapping in Refractory Epilepsy Using Magnetoencephalography
Status:
COMPLETED
Status Verified Date:
2022-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a pilot research study where language and working memory tasks will be used to study brain activities from children with epilepsy Specifically for language assessment a well-known MEG language protocol will be used and novel signal processing techniques will be applied A widely utilized paradigm will be used to study memory function and adapt signal-processing techniques from previous literature for the processing and analysis of MEG signals collected during memory task No treatmentintervention will be performed or evaluated in this pilot research study
Detailed Description:
This is a pilot research study where language and working memory tasks will be used to study brain activities from children with epilepsy Specifically for language assessment a well-known MEG language protocol will be used and novel signal processing techniques will be applied A widely utilized paradigm will be used to study memory function and adapt signal-processing techniques from previous literature for the processing and analysis of MEG signals collected during memory task No treatmentintervention will be performed or evaluated in this pilot research study
A MEG scan will be performed and data will be collected from ten pediatric subjects with drug-resistant focal epilepsy under evaluation for resective surgery If a MRI scan is available from medical records and images have the appropriate characteristics for MEG see more specifications at MRI section analysis MRI will be used for MEG source reconstruction If MRI is not available one scan will be performed MRI is necessary to obtain brain anatomy for high quality MEG source reconstruction
Quantitative parameters will be extracted from MEG data for evaluating language and memory functions This is a pilot research study where we will test the feasibility of the recording of both standard language and well-known memory task in patients with epilepsy This research is important to investigate by a non-invasive means possible patterns of language and memory organization that may in future guide surgery and limit potential loss of these functions
A MEG scan will be performed and data will be collected from ten pediatric subjects with drug-resistant focal epilepsy under evaluation for resective surgery If a MRI scan is available from medical records and images have the appropriate characteristics for MEG see more specifications at MRI section analysis MRI will be used for MEG source reconstruction If MRI is not available one scan will be performed MRI is necessary to obtain brain anatomy for high quality MEG source reconstruction
Quantitative parameters will be extracted from MEG data for evaluating language and memory functions This is a pilot research study where we will test the feasibility of the recording of both standard language and well-known memory task in patients with epilepsy This research is important to investigate by a non-invasive means possible patterns of language and memory organization that may in future guide surgery and limit potential loss of these functions
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None