Ignite Creation Date:
2024-05-06 @ 4:07 PM
Last Modification Date:
2024-10-26 @ 2:04 PM
Study NCT ID:
NCT04877509
Status:
COMPLETED
Last Update Posted:
2021-05-07
First Post:
2021-03-04
Brief Title:
Micronutrient Status Involved in Immunity in Elderly Patients With COVID-19
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Micronutrient Status Involved in Immunity in Elderly Patients With COVID-19
Status:
COMPLETED
Status Verified Date:
2021-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MicroCovAging
Brief Summary:
During the ongoing COVID-19 pandemic age was clearly the major factor of mortality Increasing age was strongly associated with this risk with the upper 80 years age group having more than 12-fold increased risk compared with those aged 50-59 years Male gender was also associated with a doubling of risk
The elderly subject is particularly exposed to global denutrition with risk of micronutrients deficiencies such as vitamins and trace elements Those deficits expose to lower immunity In addition viral infection as COVID-19 can also worsen these deficits
In general low levels or intakes of micronutrients such as Zn Se and vitamin A have been associated with adverse clinical outcomes during viral infections This notion has been confirmed in a recent review proposing that besides vitamins A and D also B vitamins vitamin C omega-3 polyunsaturated fatty acids as well as selenium zinc and iron should be considered in the assessment of micronutrients in COVID-19 patients
In this context the MicroCovAging study will evaluate copper zinc and selenium vitamin A D and E status in elderly subjects affected by COVID- 19 and to correlate this status with prognosis of this disease
The elderly subject is particularly exposed to global denutrition with risk of micronutrients deficiencies such as vitamins and trace elements Those deficits expose to lower immunity In addition viral infection as COVID-19 can also worsen these deficits
In general low levels or intakes of micronutrients such as Zn Se and vitamin A have been associated with adverse clinical outcomes during viral infections This notion has been confirmed in a recent review proposing that besides vitamins A and D also B vitamins vitamin C omega-3 polyunsaturated fatty acids as well as selenium zinc and iron should be considered in the assessment of micronutrients in COVID-19 patients
In this context the MicroCovAging study will evaluate copper zinc and selenium vitamin A D and E status in elderly subjects affected by COVID- 19 and to correlate this status with prognosis of this disease
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None