Ignite Creation Date:
2024-05-06 @ 4:07 PM
Last Modification Date:
2024-10-26 @ 2:04 PM
Study NCT ID:
NCT04875923
Status:
COMPLETED
Last Update Posted:
2024-03-19
First Post:
2021-04-21
Brief Title:
Cardiac Surgery as a Means of Reversing Frailty
Sponsor:
Dr Valerie-Anna Rudas
Organization:
Medical University of Vienna
Study Overview
Official Title:
Cardiac Surgery as a Means of Reversing Frailty - The CURE-Frailty Trial
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CURE-Frailty
Brief Summary:
Frailty is a multifactorial condition associated with older age which leads to increased vulnerability to external stressors such as infections or surgical procedures Key features of frailty are unintentional weight loss reduced strength and physical activity as well as the feeling of exhaustion
When selecting patients for surgery frailty can play an important part in resource planning and prognostication Multiple studies have shown frailty to have a negative impact on mortality perioperative adverse events hospital length of stay as well as postoperative quality of life and functional status Despite it being an important patient-centered outcome postoperative quality of life tends to be overlooked when selecting patients for surgery
Cardiac surgery presents a massive stressor to the frail patient but on the other hand might have the ability to reduce disease burden and improve functional status thus reducing frailty
This prospective observational cohort study aims to assess frailty as well as functional status and quality of life in cardiosurgical patients pre- and postoperatively and evaluate its impact on postoperative clinical and functional outcomes
The primary endpoint of this study is the change in postoperative level of frailty
When selecting patients for surgery frailty can play an important part in resource planning and prognostication Multiple studies have shown frailty to have a negative impact on mortality perioperative adverse events hospital length of stay as well as postoperative quality of life and functional status Despite it being an important patient-centered outcome postoperative quality of life tends to be overlooked when selecting patients for surgery
Cardiac surgery presents a massive stressor to the frail patient but on the other hand might have the ability to reduce disease burden and improve functional status thus reducing frailty
This prospective observational cohort study aims to assess frailty as well as functional status and quality of life in cardiosurgical patients pre- and postoperatively and evaluate its impact on postoperative clinical and functional outcomes
The primary endpoint of this study is the change in postoperative level of frailty
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None